Interleukin-5 (IL-5), also known as B-cell growth factor II (BCGF-II) and T-cell replacing factor (TRF), is a glycosylated homodimer with two disulfide bonds. IL-5 is mainly produced by eosinophils and Th2 cells, and its main function is to induce terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. The IL-5 receptor consists of α and βc subunits with IL-5 initially binding to the α subunit with low affinity and then associating with the βc subunit homodimer to yield a high affinity interaction. IL-5 is associated with eosinophilia and other disorders.


IL-5 Singleplex Products

Our IL-5 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of IL-5. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.


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