V-PLEX Plus Rat IL-5 Kit


Rat interleukin-5 (IL-5), also known as B-cell growth factor II (BCGF-II) and T-cell replacing factor (TRF), is a glycosylated homodimer with two disulfide bonds and a monomeric molecular weight around 15.2 kDa. It is mainly produced by eosinophils and Th2 cells, and its primary function is to induce terminal differentiation of late-developing B-cells into immunoglobulin-secreting cells. The IL-5 receptor consists of α and βc subunits with IL-5 initially binding to the α subunit with low affinity and then associating with the βc subunit homodimer to yield a high-affinity interaction. IL-5 is associated with eosinophilia and other disorders.The Rat IL-5 Kit provides assay-specific components for the quantitative determination of endogenous IL-5 in rat urine, serum, plasma, and cell culture supernatants.

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1 plate
5 plates
25 plates
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