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V-PLEX Viral Panel 3 NHP Kit

The V-PLEX platform offers analytically validated singleplex and multiplex assay kits. Developed under rigorous design control, V-PLEX kits provide accurate and reproducible results with consistency from lot to lot. The V-PLEX Viral Panel 3 (NHP) Kit includes six biomarkers that are associated with the immune response to viral infection (Table 1). The assays can be used for quantitative measurements of the sample type(s) listed in the “Specifications” tab below and offer detection limits (LLODs and LLOQs) in the sub- to low pg/mL range.

Table 1. List of analytes and typical detection limits

Analyte	LLOD	LLOQ	ULOQ	Dynamic Range	Unit
IFN-γ	0.37	1.76	938	0.37 - 938	pg/mL
IL-1β	0.05	0.646	375	0.05 - 375	pg/mL
IL-5	0.14	4.41	562	0.14 - 562	pg/mL
IL-6	0.06	0.633	488	0.06 - 488	pg/mL
IL-8	0.07	0.591	375	0.07 - 375	pg/mL
IL-10	0.04	0.298	233	0.04 - 233	pg/mL

Specifications
Kit Contents
Documentation
References

Application(s)		Cytokines & Chemokines , Immunology/Inflammation
Analyte(s)		IFN-γ, IL-1β, IL-5, IL-6, IL-8, IL-10
Species		Non-human primate
Instrument		MESO QuickPlex SQ 120 , MESO QuickPlex SQ 120MM , MESO SECTOR S 600 , MESO SECTOR S 600MM , SECTOR Imager 2400 , SECTOR Imager 6000
Plate Type		96-well
Sample Type		Serum, Plasma, Urine, Cell Culture Supernatant
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Condition		Multi-Component

Kit Contents for Catalog No. K15350D-1

Product Description

Storage

Quantity per Kit

V-PLEX Viral Panel (NHP) Kit (subplexed V-PLEX Proinflammatory Panel 1 NHP Kit)

Multi-Component

1 each
(1 plate size)

Proinflammatory Panel 1 (human) Calibrator Blend	2-8 °C	1 vial (1 vial)
SULFO-TAG Human IL-1β Antibody	2-8 °C	1 vial (75 μL)
SULFO-TAG Human IL-6 Antibody	2-8 °C	1 vial (75 μL)
SULFO-TAG Human IL-8 Antibody	2-8 °C	1 vial (75 μL)
SULFO-TAG Human IFN-γ Antibody	2-8 °C	1 vial (75 μL)
SULFO-TAG Human IL-10 Antibody	2-8 °C	1 vial (75 μL)
Proinflammatory Panel 1 (human) Plate	2-8 °C	1 each (1 plate)
Diluent Assembly 1 (includes Diluent 2 – 8 mL, Diluent 3 – 5 mL)	≤-10 °C	1 each
Read Buffer T 4X	RT	1 bottle (50 mL)

V-PLEX NHP IL-5 Kit

Multi-Component

1 each
(1 plate size)

Kit Contents for Catalog No. K15350D-2

Product Description

Storage

Quantity per Kit

V-PLEX Viral Panel (NHP) Kit (subplexed V-PLEX Proinflammatory Panel 1 NHP Kit)

Multi-Component

1 each
(5 plate size)

Proinflammatory Panel 1 (human) Calibrator Blend	2-8 °C	5 vial (1 vial)
SULFO-TAG Human IL-1β Antibody	2-8 °C	1 vial (375 μL)
SULFO-TAG Human IL-6 Antibody	2-8 °C	1 vial (375 μL)
SULFO-TAG Human IL-8 Antibody	2-8 °C	1 vial (375 μL)
SULFO-TAG Human IFN-γ Antibody	2-8 °C	1 vial (375 μL)
SULFO-TAG Human IL-10 Antibody	2-8 °C	1 vial (375 μL)
Proinflammatory Panel 1 (human) Plate	2-8 °C	5 each (1 plate)
Diluent Assembly 2 (includes Diluent 2 – 40 mL, Diluent 3 – 25 mL)	≤-10 °C	1 each
Read Buffer T 4X	RT	1 bottle (50 mL)

V-PLEX NHP IL-5 Kit

Multi-Component

1 each
(5 plate size)

Kit Contents for Catalog No. K15350D-4

Product Description

Storage

Quantity per Kit

V-PLEX Viral Panel (NHP) Kit (subplexed V-PLEX Proinflammatory Panel 1 NHP Kit)

Multi-Component

1 each
(25 plate size)

Proinflammatory Panel 1 (human) Calibrator Blend	2-8 °C	25 vial (1 vial)
SULFO-TAG Human IL-1β Antibody	2-8 °C	5 vial (375 μL)
SULFO-TAG Human IL-6 Antibody	2-8 °C	5 vial (375 μL)
SULFO-TAG Human IL-8 Antibody	2-8 °C	5 vial (375 μL)
SULFO-TAG Human IFN-γ Antibody	2-8 °C	5 vial (375 μL)
SULFO-TAG Human IL-10 Antibody	2-8 °C	5 vial (375 μL)
Proinflammatory Panel 1 (human) Plate	2-8 °C	25 each (1 plate)
Diluent Assembly 2 (includes Diluent 2 – 40 mL, Diluent 3 – 25 mL)	≤-10 °C	5 each
Read Buffer T 4X	RT	5 bottle (50 mL)

V-PLEX NHP IL-5 Kit

Multi-Component

1 each
(25 plate size)

Product Inserts		V-PLEX Cytokine Panel 1 Human Calibrator Insert V-PLEX Cytokine Panel 1 NHP Product Insert V-PLEX Proinflammatory Panel 1 NHP Product Insert
SDS		Diluent 2, Diluent 3, Diluent 5, Diluent 7 and Diluent 8 Diluent 41, Diluent 43 and Diluent 45 MSD Calibrators and Controls Read Buffer T (4x), Read Buffer S (4x) and Read Buffer S (1x)

Title	Journal	Year
Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms Arvid Edén, Anna Grahn, Daniel Bremell, Anahit Aghvanyan, Pradeepthi Bathala, Dietmar Fuchs, Johanna Gostner, Lars Hagberg, Nelly Kanberg, Sunsanee Kanjananimmanont, Magnus Lindh, Salvia Misaghian, Staffan Nilsson, Michael Schöll, George Sigal, Erika Stentoft, Marie Studahl, Aylin Yilmaz, Mingyue Wang, Martin Stengelin, Henrik Zetterberg, Magnus Gisslén	JAMA Network Open	2022
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations Bing Sun, Norina Tang, Michael J. Peluso, Nikita S. Iyer, Leonel Torres, Joanna L. Donatelli, Sadie E. Munter, Christopher C. Nixon, Rachel L. Rutishauser, Isabel Rodriguez-Barraquer, Bryan Greenhouse, John D. Kelly, Jeffrey N. Martin, Steven G. Deeks, Timothy J. Henrich, and Lynn Pulliam	Cells	2021
Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection Najmeh Bozorgmehr, Siavash Mashhouri, Eliana Perez Rosero, Lai Xu, Shima Shahbaz, Wendy Sligl, Mohammed Osman, Demetrios J. Kutsogiannis, Erika MacIntyre, Conar R. O’Neil, Shokrollah Elahi	mBio	2021
IL-6 as a Mediator of the Association Between Traditional Risk Factors and Future Myocardial Infarction: A Nested Case-Control Study Mulugeta M Zegeye, Jonas S O Andersson, Patrik Wennberg, Dirk Repsilber, Allan Sirsjö, Liza U Ljungberg	Arteriosclerosis, Thrombosis, and Vascular Biology	2021
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, Xue Manz, Jurjan Aman, Amsterdam UMC COVID-19 Biobank, Peter Bonta, Philip Brouwer, Steven de Taeye, Tom Caniels, Karlijn van der Straten, Korneliusz Golebski, Guillermo Griffith, René Jonkers, Mads Larsen, Federica Linty, Annette Neele, Jan Nouta, Frank van Baarle, Cornelis van Drunen, Alexander Vlaar, Godelieve de Bree, Rogier Sanders, Lisa Willemsen, Manfred Wuhrer, Harm Jan Bogaard, Marit van Gils, Gestur Vidarsson, Menno de Winther, Jeroen den Dunnen	TBD	2020
View All

Related Products

Product Name	Applications	Species	Plate Type
V-PLEX Plus Viral Panel 3 NHP Kit	Cytokines & Chemokines, Immunology/Inflammation	Non-human primate	96-well

Order Details

Catalog No

Size

Price in USD

Qty

K15350D-1

1 plate size

$1,475.00

Not Applicable

K15350D-2

5 plate size

$6,234.00

Not Applicable

K15350D-4

25 plate size

$27,482.00

Not Applicable

Please enter a quantity for the product size you would like to add to cart.

Error detected: MSD has transitioned this product to a status of “made-to-order” with a minimum order size of 25 plates. For an order of the 5-plate pack size, the minimum quantity is 5 packs (25 plates).

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V-PLEX Viral Panel 3 NHP Kit

Kit Contents for Catalog No. K15350D-1

Kit Contents for Catalog No. K15350D-2

Kit Contents for Catalog No. K15350D-4

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