IL-10

Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is a glycosylated homodimeric cytokine with two disulfide bonds. It is produced by a variety of cell lines such as T-cells, macrophages, and mast cells. The homodimer binds to two IL-10 Rα subunits resulting in recruitment of two IL-10 Rβ chains to initiate the IL-10 mediated signal cascades. IL-10 Rβ is also associated with receptors of IL-22, IL-26, IL-28, and IL-29. IL-10 is involved in the inhibition of numerous cytokine syntheses, including IFN-γ, IL-2, IL-3, TNF-α, TNF-β, and GM-CSF, that suppress Th1 proinflammatory responses and promote phagocytic uptake. IL-10 has been shown to prevent liver necrosis during parasitic infection in mice

 

IL-10 Singleplex Products

Our IL-10 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of IL-10. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

View All
IL-10 Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

View All
Related Custom Assays

The following related assays are not in our catalog but may be available as custom orders. Custom orders are typically shipped in 3 to 6 weeks. You may request pricing and availability for the assays below using our Custom Assay Quote Request form.

  • IL-10 - Rat
Browse Our Products

By Analytes
By Applications
Search
Customer Service/Orders


Scientific/Technical Support


Instrument Support


Company Headquarters