V-PLEX Plus Human IL-10 Kit

Human interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is a 20.5 kDa, glycosylated homodimeric cytokine with two disulfide bonds. The homodimer binds to two IL-10 Rα subunits resulting in recruitment of two IL-10 Rβ chains to initiate the IL-10 mediated signal cascades. IL-10 Rβ is also associated with receptors of IL-22, IL-26, IL-28, and IL-29. IL-10 inhibits the synthesis of numerous cytokines (including IFN-γ, IL-2, IL-3, TNF-α, TNF-β, and GM-CSF) that suppress Th1 proinflammatory responses and promote phagocytic uptake. IL-10 has been shown to prevent liver necrosis during parasitic infection in mice.The Human IL-10 Kit provides the assay-specific components for the quantitative determination of endogenous IL-10 in human urine, serum, plasma, and cell culture supernatants.

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Order Details
Catalog No
Size
Price in USD
Qty
K151QUG-1
1 plate
$557.00
K151QUG-2
5 plates
$2,365.00
K151QUG-4
25 plates
$9,970.00
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