V-PLEX GLP-1 Active Kit


V-PLEX GLP-1 Active Kit Overview
The V-PLEX GLP-1 Active Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX GLP-1 Active Kit enables the sensitive detection of native active GLP-1 in multiple sample types, including plasma and cell culture supernatants, across 5 species; human, mouse, rat, NHP and canine. To learn more about the advantages of V-PLEX assays click here.

All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis. V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.

V-PLEX GLP-1 Active Assay Features
  • Validated to measure Active GLP-1 in plasma and cell culture supernatants in 5 species; human, mouse, rat, NHP and canine
  • Dynamic range: 0.02 – 120 pM
  • LLOQ: 0.3 pM

Typical Data
Calibration curve for the V-PLEX GLP-1 Active Kit was assessed and representative data is presented below.

Figure 1. V-PLEX GLP-1 Active Kit Calibration Curve
Calibration Curve for V-PLEX GLP-1 Active Kit
GLP-1 Active Analyte

Description - Description - Glucagon-like peptide-1 (GLP-1), a post-translational product of preproglucagon, is a protein hormone produced in intestinal L cells that plays a key role in the promotion of glucose-dependent insulin secretion and insulin biosynthesis. GLP-1 works in concert with insulin to inhibit glucose secretion and lower overall blood glucose levels. The cleaved peptides, commonly referred to as GLP-1 (7-36) amide and GLP-1 (7-37) are the biologically active forms of GLP-1. In vivo, these active isoforms are rapidly cleaved by dipeptidyl peptidase IV (DPPIV). The primary amino acid sequence for GLP-1 is conserved among mammalian species, i.e. human, mouse, rat, monkey, canine, etc.

Disease Research Area - Metabolic Diseases

Application Area - Metabolic, Cardiovascular

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1 plate
5 plates
25 plates
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