spot difference
  • Sign In
  • Register
  • Cart (0)
Home > Products & Services > Assay Kits > V-PLEX Assay Platform > V-PLEX-Metabolic Assays

V-PLEX-Metabolic Assays

New V-PLEX Metabolic Assay Panels

 

V-PLEX: MSD’s Validated Assay Platform

V-PLEX validated assays deliver reproducibility and reliability to support the most demanding long-term studies. V-PLEX assays maximize consistency in results and confidence in data.

Biomarker Assays for Obesity, Diabetes, and Metabolic-Related Research Areas

The complex pathologies of diabetes, cardiovascular disease, and metabolic syndrome have driven an increased demand for quantitative measurement of biomarkers associated with these disease states. Obesity is directly related to increased risk for diabetes, hypertension, atherosclerosis, and metabolic syndrome. Novel proteomic technologies have helped define key serum biomarkers produced in the gut and adipose tissue and altered in abundance in disease states.

Accelerate your metabolic research with the quality and performance you expect from MSD. V-PLEX metabolic assays are available as validated individual assays (Table 1) or as a part of a validated multiplex panel (Table 2). For greater convenience, metabolic assays that show cross-reactivity are offered as species-specific panels. V-PLEX metabolic assays have wide dynamic range and provide greater sensitivity, as shown in the table below.


 

Click the button to create your custom multiplex panels or subset multiplexes from a pre-configured panel.


Table 1. Individual Assays of Metabolic Analytes
Analytes Human Mouse NHP Rat Canine
Insulin ●   ●   ●
C-Peptide ●   ●    
GLP-1 (active) ● ● ● ● ●
GIP (active) ●   ● ● ●
Glucagon ● ● ● ● ●
PP ●   ●    
Leptin ●        

Dynamic Range
Assay LLOD - ULOQ
Insulin 0.006 - 19.5 μIU/mL
C-Peptide 4.72 - 3,150 pg/mL
GLP-1 (active) 0.011 - 39 pM
GIP (active) 0.233 - 390 pg/mL
Glucagon 0.015 - 52 pM
PP 0.043 - 325 pg/mL
Leptin 5.78 - 7,150 pg/mL

All V-PLEX kits come with coated plates, calibrators, individual labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis. V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.


Table 2. Species-specific Metabolic Panels
V-PLEX Metabolic Panel Kits V-PLEX Cat. # V-PLEX Plus Cat. # Analytes
Metabolic Panel 1 (human) K15325D K15325G C-Peptide, GIP (active), GLP-1 (active), Glucagon, Insulin, Leptin, and PP
Metabolic Panel 1 (mouse) K15333D K15333G GLP-1 (active) and Glucagon
Metabolic Panel 1 (NHP) K15332D K15332G C-Peptide, GIP (active), GLP-1 (active), Glucagon, Insulin, and PP
Metabolic Panel 1 (rat) K15334D K15334G GIP (active), GLP-1 (active), and Glucagon
Metabolic Panel 1 (canine) K15335D K15335G GIP (active), GLP-1 (active), Glucagon, and Insulin