R-PLEX Human Thrombomod. Antibody Set

R-PLEX Human Thrombomod. Antibody Set Overview
The R-PLEX Human Thrombomod. Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Thrombomodulin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Thrombomod. Antibody Set Features
  • Measures human Thrombomodulin in serum, plasma, and urine
  • Dynamic range: 2.1 - 200,000 pg/mL
  • Median LLOD: 2.1 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Thrombomod. Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Thrombomod. Antibody Set Calibration Curve
Calibration curve for R-PLEX Human Thrombomod. Antibody Set
Thrombomod. Analyte

Description - Thrombomodulin (TM, THRM, AHUS6, BDCA3, THPH12, THBD, CD141) is an endothelial cell surface receptor glycoprotein and an essential cofactor for active thrombin. Thrombomodulin is expressed on the surface of a variety of cell types such as monocytes, mesothelial and dendritic cells. Mutations in the TM gene can be associated with inherited thrombophilia and atypical hemolytic-uremic syndrome. Thrombomodulin is also known to play a role in thrombosis, arteriosclerosis, stroke, and cancer.

Disease Research Area - Stroke, Cancer, Arteriosclerosis

Application Area - Cardiovascular, Homeostasis

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5 plate size
50 plate size
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