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Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic alpha(2)-receptor levels in a transgenic Huntington's disease rat model.
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Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo
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Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.
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Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice.
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Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.
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Longitudinal cytokine expression during IMRT for prostate cancer and acute treatment toxicity.
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Matrix metalloproteinases: discrete elevations in essential hypertension and hypertensive end-stage renal disease.
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Measurement of ERK 1/2 in CSF from Patients with Neuropsychiatric Disorders and Evidence for the Presence of the Activated Form.
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Mechanisms of glucose homeostasis after Roux-en-Y gastric bypass surgery in the obese, insulin-resistant Zucker rat.
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Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma.
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Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen.
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Novel Tight-Binding Inhibitory Factor-kB Kinase (IKK-2) Inhibitors Demonstrate Target-Specific Anti-Inflammatory Activities in Cellular Assays and following Oral and Local Delivery in an in Vivo Model of Airway Inflammation.
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Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells.
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Optimization and validation of a multiplex, electrochemiluminescence-based detection assay for the quantitation of immunoglobulin g serotype-specific antipneumococcal antibodies in human serum.
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p38 mitogen-activated protein kinase targets the production of proinflammatory endothelial microparticles.
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Pharmacokinetic and pharmacodynamic evaluation of the suitability of using fluticasone and an acute rat lung inflammation model to differentiate lung versus systemic efficacy.
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Physical training after percutaneous coronary intervention in patients with stable angina: effects on working capacity, metabolism, and markers of inflammation.
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Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations.
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Polyanionic Microbicides Modify TLR_mediated Cervicovaginal immune response.
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PPAR-delta agonism activates fatty acid oxidation via PGC-1alpha but does not increase mitochondrial gene expression and function.
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Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase.
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Raxibacumab for the Treatment of Inhalational Anthrax.
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Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
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Reduced cerebrospinal fluid BACE1 activity in multiple sclerosis.
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Reduced levels of amyloid-beta-binding proteins in cerebrospinal fluid from Alzheimer's disease patients.
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Searching immunodominant epitopes prior to epidemic: HLA class II-restricted SARS-CoV spike protein epitopes in unexposed individuals.
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Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.
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Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians.
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Serum molecular signatures of weight change during early breast cancer chemotherapy.
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Sputum IL-5 Concentration Is Associated with a Sputum Eosinophilia and Attenuated by Corticosteroid Therapy in COPD.
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Structural details and composition of Trichomonas vaginalis lipophosphoglycan in relevance to the epithelial immune function.
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Systemic inflammation and disease progression in Alzheimer disease.
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Targeting gut T cell Ca2+ release-activated Ca2+ channels inhibits T cell cytokine production and T-box transcription factor T-bet in inflammatory bowel disease.
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Technology comparisons for anti-therapeutic antibody and neutralizing antibody assays in the context of an anti-TNF pharmacokinetic study.
Loyet, K.M., Deng, R., Liang, W.C., Wu, Y., Lowman, H.B., Deforge, L.E. | Journal of Immunological Methods | 2009 | View |
The alpha7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: A possible role for a key neurotransmitter in synovial inflammation.
Maanen, M.A., Stoof, S.P., van der Zanden, E.P., de Jonge, W.J., Janssen, R.A., Fischer, D.F., Vandeghinste, N., Brys, R., Vervoordeldonk, M.J., Tak, P.P. | Arthritis Rheum. | 2009 | View |
The hydrophobic tunnel present in LOX-1 is essential for oxidized Low-density lipoprotein recognition and binding.
Francone, O.L., Tu, M., Royer, L.J., Zhu, J., Stevens, K., Oleynek, J.J., Lin, Z., Shelley, L., Sand, T., Luo, Y., Kane, C.D. | J Lipid Res. | 2009 | View |
The impact of Fc engineering on an anti-CD19 antibody: increased Fcgamma receptor affinity enhances B-cell clearing in nonhuman primates.
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The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain
Lien, L.F., Haqq, A.M., Arlotto, M., Slentz, C.A., Muehlbauer, M.J., McMahon, R.L., Rochon, J., Gallup, D., Bain, J.R., Ilkayeva, O., Wenner, B.R., Stevens, R.D., Millington, D.S., Muoio, D.M., Butler, M.D., Newgard, C.B., Svetkey, L.P. | OMICS. | 2009 | View |
Trans fat feeding results in higher serum alanine aminotransferase and increased insulin resistance compared with a standard murine high-fat diet.
Koppe, S.W., Elias, M., Moseley, R.H., Green, R.M. | Am J Physiol Gastrointest Liver Physiol. | 2009 | View |
TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines.
Kuai, J., Gregory, B., Hill, A., Pittman, D.D., Feldman, J.L., Brown, T., Carito, B., O'Toole, M., Ramsey, R., Adolfsson, O., Shields, K.M., Dower, K., Hall, J.P., Kurdi, Y., Beech, J.T., Nanchahal, J., Feldmann, M., Foxwell, B.M., Brennan, F.M., Winkler, D.G., Lin, L.L. | Rheumatology (Oxford). | 2009 | View |
Tumour necrosis factor a mediates transient receptor potential vanilloid 1-dependent bilateral thermal hyperalgesia with distinct peripheral roles of interleukin-1ß, protein kinase C and cyclooxygenase-2 signaling.
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