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Development of a Rapid Streptavidin Capture-Based Assay for the Tyrosine Phosphorylated CSF-1R in Peripheral Blood Mononuclear Cells. Chaturvedi S, Dell E, Siegel D, Brittingham G, Seetharam S. | Int J Biol Sci. | 2013 | View |
Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma. Li C, Takahashi C, Zhang L, Huseni M, Stankovich B, Mashhedi H, Lee J, French D, Anderson JE, Kim D, Howell K, Brauer MJ, Kowanetz M, Yan Y, Humke E, Ebens A, Hampton G, Lackner MR, Hegde P, Jia S. | J Transl Med | 2013 | View |
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Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression. Brouwers O, de Vos-Houben JMJ, Niessen PMG, Miyata T, van Nieuwenhoven F, Janssen BJA, Hageman G, Stehouwer CDA, Schalkwijk CG. | Int. J. Mol. Sci. | 2013 | View |
A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. | Nutr J. | 2013 | View |
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A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study. Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga TW, Allaart CF. | Rheumatology (Oxford) | 2013 | View |
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A patient with posterior cortical atrophy possesses a novel mutation in the presenilin 1 gene. Sitek EJ, Narożańska E, Pepłońska B, Filipek S, Barczak A, Styczyńska M, Mlynarczyk K, Brockhuis B, Portelius E, Religa D, Barcikowska M, Sławek J, Zekanowski C. | PLoS One | 2013 | View |
A phase 2 multicentre study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma. Voorhees PM, Manges RF, Sonneveld P, Jagannath S, Somlo G, Krishnan A, Lentzsch S, Frank RC, Zweegman S, Wijermans PW, Orlowski RZ, Kranenburg B, Hall B, Casneuf T, Qin X, van de Velde H, Xie H, Thomas SK. | Br J Haematol | 2013 | View |
A phase II and biomarker study of ramucirumab, a human monoclonal antibody targeting the VEGF receptor-2 in patients with advanced hepatocellular cancer. Zhu AX, Finn RS, Mulcahy M, Gurtler J, Sun W, Schwartz JD, Dalal RP, Joshi A, Hozak RR, Xu Y, Ancukiewicz M, Jain RK, Nugent F, Duda DG, Stuart K. | Clin Cancer Res. | 2013 | View |
A phase I/II study of ofatumumab (GSK1841157) in Japanese and Korean patients with relapsed or refractory B-cell chronic lymphocytic leukemia. Ogawa Y, Ogura M, Suzuki T, Ando K, Uchida T, Shirasugi Y, Tobinai K, Lee JH, Kase M, Katsura K, Hotta T. | Int J Hematol. | 2013 | View |
A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in patients with ankylosing spondylitis: the PLANETAS study. Park W, Hrycaj P, Jeka S, Kovalenko V, Lysenko G, Miranda P, Mikazane H, Gutierrez-Ureña S, Lim M, Lee YA, Lee SJ, Kim H, Yoo DH, Braun J. | Ann Rheum Dis. | 2013 | View |
A randomised, double-blind, parallel-group study to demonstrate equivalence in efficacy and safety of CT-P13 compared with innovator infliximab when coadministered with methotrexate in patients with active rheumatoid arthritis: the PLANETRA study. Yoo DH, Hrycaj P, Miranda P, Ramiterre E, Piotrowski M, Shevchuk S, Kovalenko V, Prodanovic N, Abello-Banfi M, Gutierrez-Ureña S, Morales-Olazabal L, Tee M, Jimenez R, Zamani O, Lee SJ, Kim H, Park W, Müller-Ladner U. | Ann Rheum Dis. | 2013 | View |
A randomized clinical trial of Behavioral Activation (BA) therapy for improving psychological and physical health in dementia caregivers: Results of the Pleasant Events Program (PEP). Moore RC, Chattillion EA, Ceglowski J, Ho J, von Känel R, Mills PJ, Ziegler MG, Patterson TL, Grant I, Mausbach BT. | Behaviour Research and Therapy | 2013 | View |
A randomized, placebo-controlled study of the pharmacokinetics, pharmacodynamics, and tolerability of the oral JAK2 inhibitor fedratinib (SAR302503) in healthy volunteers. Zhang M, Xu CR, Shamiyeh E, Liu F, Yin J, von Moltke LL, Smith WB. | J Clin Pharmacol. | 2013 | View |
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A sensitive and specific quantitation method for determination of serum cardiac Myosin binding protein-C by electrochemiluminescence immunoassay. Kuster DW, Barefield D, Govindan S, Sadayappan S. | J Vis Exp. | 2013 | View |
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Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels Lilja AM, Rojdner J, Mustafiz T, Thome CM, Storelli E, Gonzalez D, Unger-Lithner C, Greig NH, Nordberg A, Marutle A. | PLoS One | 2013 | View |
Alterations in the gut microbiota associated with HIV-1 infection. Lozupone CA, Li M, Campbell TB, Flores SC, Linderman D, Gebert MJ, Knight R, Fontenot AP, Palmer BE. | Cell Host Microbe | 2013 | View |
An Antibody Blocking Activin type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy. Lach-Trifilieff E, Minetti GC, Sheppard K, Ibebunjo C, Feige JN, Hartmann S, Brachat S, Rivet H, Koelbing C, Morvan F, Hatakeyama S, Glass DJ. | Mol Cell Biol. | 2013 | View |
An ARGS-aggrecan assay for analysis in blood and synovial fluid. Larsson S, Lohmander LS, Struglics A. | Osteoarthritis Cartilage | 2013 | View |
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An electrochemiluminescence (ECL)-based assay for the specific detection of anti-drug antibodies of the IgE isotype. Wu Y, Liu X, Chen Y, Woods R, Lee N, Yang H, Chowdhury P, Roskos LK, White WI. | Journal of Pharmaceutical and Biomedical Analysis | 2013 | View |
An exploratory evaluation of the utility of transcriptional and urinary kidney injury biomarkers for the prediction of aristolochic acid-induced renal injury in male rats. Fuchs TC, Mally A, Wool A, Beiman M, Hewitt P. | Vet Pathol. | 2013 | View |
Analysis of adult neurogenesis: Evidence for a prominent “Non-Neurogenic” DCX-Protein pool in rodent brain. Kremer T, Jagasia R, Herrmann A, Matile H, Borroni E, Francis F, Kuhn HG, Czech C. | PLoS One | 2013 | View |
Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection. Osburn WO, Levine JS, Chattergoon MA, Thomas DL, Cox AL. | Journal of Viral Hepatitis | 2013 | View |
Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS. Gendron TF, Bieniek KF, Zhang YJ, Jansen-West K, Ash PE, Caulfield T, Daughrity L, Dunmore JH, Castanedes-Casey M, Chew J, Cosio DM, van Blitterswijk M, Lee WC, Rademakers R, Boylan KB, Dickson DW, Petrucelli L. | Acta Neuropathol. | 2013 | View |
Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics. Burt D, Crowell SJ, Ackley DC, Magee TV, Aubrecht J. | Drug Chem Toxicol. | 2013 | View |
Assessment of an anti-alpha toxin mAb for prevention and treatment of Staphylococcus aureus induced pneumonia. Hua L, Hilliard JJ, Shi Y, Tkaczyk C, Cheng LI, Yu X, Datta A, Ren S, Feng H, Zinsou R, Keller A, O'Day T, Du Q, Cheng L, Damschroder M, Robbie G, Suzich J, Stover CK, Sellman BR. | Antimicrob Agents Chemother. | 2013 | View |
Assessment of cisplatin-induced kidney injury using an integrated rodent platform. Chen Y, Brott D, Luo W, Gangl E, Kamendi H, Barthlow H, Lengel D, Fikes J, Kinter L, Valentin JP, Bialecki R. | Toxicol Appl Pharmacol | 2013 | View |
Association of circulating sclerostin with bone mineral mass, microstructure, and turnover biochemical markers in healthy elderly men and women. Durosier C, Van Lierop A, Ferrari S, Chevalley T, Papapoulos S, Rizzoli R. | J Clin Endocrinol Metab. | 2013 | View |
Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: A preliminary report. Ross H, Guo Y, Coleman K, Ousley O, Miller A. | Brain Behav Immun | 2013 | View |
Associations between Maternal and Infant Morbidities and sRAGE within the First Week of Life in Extremely Preterm Infants. Rogers LK, Graf AE, Bhatia A, Leonhart KL, Oza-Frank R. | PLoS One | 2013 | View |
Associations of interleukin-6 with vegetative but not affective depressive symptoms in terminally ill cancer patients. Inagaki M, Akechi T, Okuyama T, Sugawara Y, Kinoshita H, Shima Y, Terao K, Mitsunaga S, Ochiai A, Uchitomi Y. | Support Care Cancer | 2013 | View |
ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions. A method to directly monitor the active conformation of LRRK2? Gillardon F, Kremmer E, Froehlich T, Ueffing M, Hengerer B, Gloeckner CJ. | J Neurosci Methods | 2013 | View |
AZ-4217: A high potency BACE inhibitor displaying acute central efficacy in different In vivo models and reduced amyloid deposition in Tg2576 mice. Eketjäll S, Janson J, Jeppsson F, Svanhagen A, Kolmodin K, Gustavsson S, Radesäter AC, Eliason K, Briem S, Appelkvist P, Niva C, Berg AL, Karlström S, Swahn BM, Fälting J. | J Neurosci. | 2013 | View |
Bacillus anthracis protective antigen kinetics in inhalation spore-challenged untreated or Levofloxacin/ Raxibacumab-treated New Zealand White rabbits. Corey A, Migone TS, Bolmer S, Fiscella M, Ward C, Chen C, Meister G. | Toxins | 2013 | View |
Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice. Vasu S, Moffett RC, McCluskey JT, Hamid MH, Irwin N, Flatt PR. | Gene Ther. | 2013 | View |
BET bromodomain inhibition suppresses TH17-mediated pathology. Mele DA, Salmeron A, Ghosh S, Huang HR, Bryant BM, Lora JM. | J Exp Med. | 2013 | View |
β-Defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-α production by human plasmacytoid dendritic cells, and promote inflammation. Tewary P, de la Rosa G, Sharma N, Rodriguez LG, Tarasov SG, Howard OM, Shirota H, Steinhagen F, Klinman DM, Yang D, Oppenheim JJ. | J Immunol. | 2013 | View |
Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut. Groeger D, O'Mahony L, Murphy EF, Bourke JF, Dinan TG, Kiely B, Shanahan F, Quigley EM. | Gut Microbes. | 2013 | View |