| References | Journal | Year | |
IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma.
Calvo, K.R., Dabir, B., Kovach, A., Devor, C., Bandle, R., Bond, A., Shih, J.H., Jaffe, E.S. | Blood | 2008 | View |
Immuno's Logical - Drug developers turn to the new and established immunoassay platforms to measure and identify protein biomarkers.
Netterwald, J. | Drug Disc Devel. | 2008 | View |
Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels.
Riddell, D.R., Zhou, H., Atchison, K., Warwick, H.K., Atkinson, P.J., Jefferson, J., Xu, L., Aschmies, S., Kirksey, Y., Hu, Y., Wagner, E., Parratt, A., Xu, J., Li, Z., Zaleska, M.M., Jacobsen, J.S., Pangalos, M.N., Reinhart, P.H. | J Neurosci. | 2008 | View |
Impact of cholesterol level upon APP and BACE proximity and APP cleavage.
von Arnim, C.A., von Einem, B., Weber, P., Wagner, M., Schwanzar, D., Spoelgen, R., Strauss, W.L., Schneckenburger, H. | Biochem Biophys Res Commun. | 2008 | View |
Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED.
Ryan, K.R., Hong, M., Arkwright, P.D., Gennery, A.R., Costigan, C., Dominguez, M., Denning, D., McConnell, V., Cant, A.J., Abinun, M., Spickett, G.P., Lilic, D. | Clin Exp Immunol. | 2008 | View |
Influenza A virus inhibits alveolar fluid clearance in BALB/c mice.
Wolk, K.E., Lazarowski, E.R., Traylor, Z.P., Yu, E.N., Jewell, N.A., Durbin, R.K., Durbin, J.E., Davis, I.C. | Am J Respir Crit Care Med. | 2008 | View |
Inhibiting Hdm2 and Ubiquitin-Activating Enzyme: Targeting the Ubiquitin Conjugating System in Cancer.
Weissman, A.M., Yang, Y., Kitagaki, J., Sasiela, C.A., Beutler, J.A., O'Keefe, B.R. | The Ubiquitin System in Health and Disease. Springer Berlin Heidelberg. | 2008 | View |
Innate Immune Responses to TREM-1 Activation: Overlap, Divergence, and Positive and Negative Cross-Talk with Bacterial Lipopolysaccharide.
Dower, K., Ellis, D.K., Saraf, K, Jelinsky, S.A., Lin, L.L. | J Immunol Methods | 2008 | View |
Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology.
Dao, J.H., Kurzeja, R.J., Morachis, J.M., Veith, H., Lewis, J., Yu, V., Tegley, C.M., Tagari, P. | Anal Biochem. | 2008 | View |
Lack of FFAR1/GPR40 Does Not Protect Mice From High-Fat Diet-Induced Metabolic Disease.
Lan, H., Hoos, L.M., Liu, L., Tetzloff, G., Hu, W., Abbondanzo, S.J., Vassileva, G., Gustafson, E.L., Hedrick, J.A., Davis, H.R. | Diabetes | 2008 | View |
Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.
de la Rosa, G., Yang, D., Tewary, P., Varadhachary, A., Oppenheim, J.J. | J Immunol Methods | 2008 | View |
Liver TAG transiently decreases while PL n-3 and n-6 fatty acids are persistently elevated in insulin resistant mice.
Scheja, L., Toedter, K., Mohr, R., Niederfellner, G., Michael, M.D., Meissner, A., Schoettler, A., Pospisil, H., Beisiegel, U., Heeren, J. | Lipids. | 2008 | View |
mall-Molecule Inhibitors of PDK1.
Peifer, C., Alessi, D.R. | ChemMedChem. | 2008 | View |
MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult.
Thompson, W.L., Karpus W.J., Van Eldik, L.J. | J Neuroinflammation. | 2008 | View |
Measurement of bovine somatotropin (bST) and insulin-like growth factor-1 (IGF-1) in bovine milk using an electrochemiluminescent assay.
McGrath, M.F., Bogosian, G., Fabellar, A.C., Staub, R.L., Vicini, J.L., Widger, L.A. | J Agric Food Chem. | 2008 | View |
Measuring the tyrosine kinase activity: a review of biochemical and cellular assay technologies.
Jia, Y., Gu, X., Brinker, A., Warmuth, M. | Expert Opinion on Drug Discovery. | 2008 | View |
Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742.
Haskova, Z., Hoang, B., Luo, G., Morgan, L.A., Billin, A.N., Barone, F.C., Shearer, B.G., Barton, M.E., Kilgore, K.S. | Inflamm Res. | 2008 | View |
Mutual antagonistic relationship between prostaglandin E(2) and IFN-gamma: Implications for rheumatoid arthritis.
Mathieu, M.C., Lord-Dufour, S., Bernier, V., Boie, Y., Burch, J.D., Clark, P., Denis, D., Han, Y., Mortimer, J.R., Therien, A.G. | Eur J Immunol. | 2008 | View |
Neurochemical dementia diagnostics: State of the art and research perspectives.
Lewczuk P, Wiltfang J. | Proteomics | 2008 | View |
New technologies around biomarkers and their interplay with drug development.
Dieterle, F., Marrer, E. | Anal Bioanal Chem. | 2008 | View |
New technologies for diagnosing pediatric tumors.
Wei, J.S., Badgett, T.C., Khan, J. | Expert Opin Med Diagn. | 2008 | View |
Novel technologies for the discovery and quantitation of biomarkers of toxicity.
Collings, F.B., Vaidya, V.S. | Toxicology. | 2008 | View |
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
Eccles, S.A., Massey, A., Raynaud, F.I., Sharp, S.Y., Box, G., Valenti, M., Patterson, L., de Haven Brandon, A., Gowan, S., Boxall, F., Aherne, W., Rowlands, M., Hayes, A., Martins, V., Urban, F., Boxall, K., Prodromou, C., Pearl, L., James, K., Matthews, T.P., Cheung, K.M., Kalusa, A., Jones, K., McDonald, E., Barril, X., Brough, P.A., Cansfield, J.E., Dymock, B., Drysdale, M.J., Finch, H., Howes, R., Hubbard, R.E., Surgenor, A., Webb, P., Wood, M., Wright, L., Workman, P. | Cancer Res. | 2008 | View |
Omega-3 fatty acids effect on wound healing.
McDaniel, J.C., Belury, M., Ahijevych, K., Blakely, W. | Wound Repair Regen. | 2008 | View |
Peripheral elevation of IGF-1 fails to alter Ab clearance in multiple in vivo models.
Lanz, TA., Salatto, C.T., Semproni, AR., Marconi, M., Brown, TM., Richter, KE., Schmidt, K., Nelson, FR., Schachter, JB., | Biochemical Pharmacology | 2008 | View |
Pharmacological properties of SD-282 - an alpha-isoform selective inhibitor for p38 MAP kinase.
Koppelman, B., Webb, H.K., Medicherla, S., Almirez, R., Feng, Y., Chavez, J.C., Mao, C.P., Nguyen, A., Liu, Y.W., Kapoun, A.M., Muiru, G., Huang, Y.A., Dugar, S., Mavunkel, B.J., Lim, D.W., Chakravarty, S., Luedtke, G., Protter, A.A., Higgins, L.S. | Pharmacology. | 2008 | View |
Pharmacological characterization of a small-molecule inhibitor of c-Jun kinase.
Cho, H.K., Black, S.C., Looper, D., Shi, M., Kelly-Sullivan, D., Timofeevski, S., Siegel, K., Yu, X.H., McDonnell, S.R., Chen, P., Yie, J., Ogilvie, K.M., Fraser, J., Briscoe, C.P. | Am J Physiol Endocrinol Metab. | 2008 | View |
Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets.
Waddleton, D., Wu, W., Feng, Y., Thompson, C., Wu, M., Zhou, Y.P., Howard, A., Thornberry, N., Li, J., Mancini, J.A. | Biochemical Pharmacology | 2008 | View |
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model.
Cacucci ,F., Yi M., Wills, T.J., Chapman, P., O'Keefe, J. | PNAS | 2008 | View |
Plasma PCSK9 Concentrations Correlate with LDL and Total Cholesterol in Diabetic Patients and Are Decreased by Fenofibrate Treatment.
Lambert, G., Ancellin, N., Charlton, F., Comas, D., Pilot, J., Keech, A., Patel, S., Sullivan, D.R., Cohn, J.S., Rye, K.A., Barter, P.J. | Clin Chem. | 2008 | View |
Practical approaches to proteomic biomarkers within prostate cancer radiotherapy trials.
Christensen, E., Evans, K.R., Menard, C., Pintilie, M., Bristow, R.G. | Cancer Metastasis Rev. | 2008 | View |
Protein kinase B/Akt activity is involved in renal TGF-{beta}1-driven epithelial-mesenchymal transition in vitro and in vivo.
Kattla, J.J., Carew, R.M., Heljic, M., Godson, C., Brazil, D.P. | Am J Physiol Renal Physiol. | 2008 | View |
Protein Microarray Technologies for Detection and Identification of Bacterial and Protein Analytes in Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems.(Book Chapter)
Wingren, C., Borrebaeck, C.A.K. | ed. Zourob, M. | 2008 | View |
Reactivation of human herpesvirus-6 in natalizumab treated multiple sclerosis patients.
Yao, K., Gagnon, S., Akhyani, N., Williams, E., Fotheringham, J., Frohman, E., Stuve, O., Monson, N., Racke, M.K., Jacobson, S. | PLoS ONE | 2008 | View |
Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response.
Lee, J.K., McCoy M.K, Harms, A.S, Ruhn, K.A., Gold S.J., Tansey M.G. | J Neurosci. | 2008 | View |
RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice.
Yang, B., Trump, R.P., Shen, Y., McNulty, J.A., Clifton, L.G., Stimpson, S.A., Lin, P., Pahel, G.L. | BMC Pharmacology. | 2008 | View |
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial.
Lannfelt, L., Blennow, K., Zetterberg, H., Batsman, S., Ames, D., Harrison, J., Masters, C.L., Targum, S., Bush, A.I., Murdoch, R., Wilson, J., Ritchie, C.W., PBT2-201-EURO study group. | Lancet Neurol. | 2008 | View |
Simultaneous Detection of Eight Analytes in Human Serum by Two Commercially Available Platforms for Multiplex Cytokine Analysis.
Toedter, G., Hayden, K., Wagner, C., Brodmerkel, C. | Clin Vaccine Immunol. | 2008 | View |
Structural and functional characterization of disulfide isoforms of the human IGG2 subclass.
Dillon, T.M., Ricci, M.S., Vezina, C., Flynn, G.C. Liu, Y. D., Rehder, D.S., Plant, M., Henkle, B., Li, Y., Deechongkit, S., Varnum, B., Wypych, J., Balland, A., Bondarenko P. V. | J Biol Chem. | 2008 | View |
Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury.
Lloyd, E., Somera-Molina, K., Van Eldik, L.J., Watterson, D.M., Wainwright, M.S. | J Neuroinflammation. | 2008 | View |
Survey of retail milk composition as affected by label claims regarding farm-management practices.
Vicini, J, Etherton, T., Kris-Etherton, P., Ballam, J., Denham, S., Staub, R., Goldstein, D., Cady, R., McGrath, M., Lucy, M. | J Am Diet Assoc. | 2008 | View |
The anthrax vaccine adsorbed vaccine generates protective antigen (PA)-Specific CD4+ T cells with a phenotype distinct from that of naive PA T cells.
Kwok, W.W., Yang, J., James, E., Bui, J., Huston, L., Wiesen, A.R., Roti, M. | Infect Immun. | 2008 | View |
The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells.
Luqman, M., Klabunde, S., Lin, K., Georgakis, G.V., Cherukuri, A., Holash, J., Goldbeck, C., Xu, X., Kadel, E.E. 3rd, Lee, S.H., Aukerman, S.L., Jallal, B., Aziz, N., Weng, W.K., Wierda, W., O'Brien, S., Younes, A. | Blood | 2008 | View |
The identification of a small molecule inhibitor that specifically reduces T cell-mediated adaptive but not LPS-mediated innate immunity by T cell membrane-monocyte contact bioassay.
Li, Y.Y., Bao, M., Meurer, J., Skuballa, W., Bauman, J.G., Doecke, W.D., Zollner, T.M. | Immunol Lett. | 2008 | View |
The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer.
Folkes, A.J., Ahmadi, K., Alderton, W.K., Alix, S., Baker, S.J., Box, G., Chuckowree, I.S., Clarke, P.A., Depledge, P., Eccles, S.A., Friedman, L.S., Hayes, A., Hancox, T.C., Kugendradas, A., Lensun, L., Moore, P., Olivero, A.G., Pang, J., Patel, S., Pergl-Wilson, G.H., Raynaud, F.I., Robson, A., Saghir, N., Salphati, L., Sohal, S., Ultsch, M.H., Valenti, M., Wallweber, H.J., Wan, N.C., Wiesmann, C., Workman, P., Zhyvoloup, A., Zvelebil, M.J., Shuttleworth, S.J. | J Med Chem. | 2008 | View |
The p50 subunit of NF-kappaB is critical for in vivo clearance of the noninvasive enteric pathogen Citrobacter rodentium.
Dennis, A., Kudo, T., Kruidenier, L., Girard, F., Crepin, V.F., MacDonald, T.T., Frankel, G., Wiles, S. | Infect Immun. | 2008 | View |
The Stem Cell Marker CD133 (Prominin-1) Is Expressed in Various Human Glandular Epithelia.
Karbanova, J., Missol-Kolka, E., Fonseca, A.V., Lorra, C., Janich, P., Hollerova, H., Jaszai, J., Ehrmann, J., Kolar, Z., Liebers, C., Arl, S., Subrtova, D., Freund, D., Mokry, J., Huttner, W.B., Corbeil, D. | J Hist Cytochem. | 2008 | View |
The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.
Tran, T.A., McCoy, M.K., Sporn, M.B., Tansey, M.G. | J Neuroinflammation. | 2008 | View |
TLR7 Agonist 852A Inhibition of Tumor Cell Proliferation Is Dependent on Plasmacytoid Dendritic Cells and Type I IFN.
Inglefield, J.R., Dumitru, C.D., Alkan, S.S., Gibson, S.J., Lipson, K.E., Tomai, M.A., Larson, C.J., Vasilakos, J.P. | J Interferon Cytokine Res. | 2008 | View |
Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity.
Fitzgerald, P., Cassidy Eugene, M., Clarke, G., Scully, P., Barry, S., Quigley Eamonn, M.M., Shanahan, F., Cryan, J., Dinan, T. G. | Neurogastroenterol Motil. | 2008 | View |