MCP-1

Monocyte Chemoattractant Protein 1 (MCP-1, CCL2, HC11, monocyte chemotactic and activating factor, MCAF, monocyte secretory protein JE, small-inducible cytokine A2, SCYA2) is an 11 kDa glycosylated chemotactic factor. MCP-1 augments monocyte anti-tumor activity. It naturally occurs as both monomer and homodimer, and it binds to CCR2 and CCR4 receptors. MCP-1 is chemotactic for basophils and monocytes but not neutrophils or eosinophils. It stimulates mast cells and basophils to degranulate. MCP-1 is elevated in many autoimmune disorders and is a metabokine, having functions in both the immune and metabolic systems.

 

MCP-1 Singleplex Products

Our MCP-1 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of MCP-1. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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MCP-1 Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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