C-Reactive Protein (CRP, pentraxin 1, PTX1) is an acute-phase member of the pentraxin family of proteins. CRP is produced by the liver in response to factors, including IL-6, released by adipocytes, T cells, and macrophages. Levels of CRP in the blood can rise more than 1000-fold in response to inflammation and other long-term diseases such as cancer, arthritis, infection of bone, and diseases of the cardiovascular and immune systems, making it relevant for research of these conditions. It activates the complement system through C1q, and initiates phagocytosis of bacteria and cells undergoing apoptosis. A correlation has been shown between high levels of CRP and stroke, heart disease, hypertension, and diabetes.


CRP Singleplex Products

Our CRP immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of CRP. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.


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