Total p53 Whole Cell Lysate Kit

p53 is a transcription factor whose activity is upregulated following DNA damage. Activation of p53 results in cell cycle arrest until DNA damage is repaired or in the activation of apoptosis if the cellular damage is too great. Mutations in the tumor suppressor p53 are found in nearly half of all human cancers. This kit provides assay-specific components for the quantitative determination of total p53 in human whole cell lysates.

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