R-PLEX Rat IL-4 Antibody Set

R-PLEX Rat IL-4 Antibody Set Overview
The R-PLEX Rat IL-4 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of IL-4 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Rat IL-4 Antibody Set Features
  • Measures rat IL-4 in serum and plasma
  • Dynamic range: 0.06 - 4,500 pg/mL
  • Median LLOD: 0.06 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Rat IL-4 Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Rat IL-4 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Rat IL-4 Antibody Set
IL-4 Analyte

Description - Interleukin-4 (IL-4, B-cell stimulatory factor 1 [BSF-1], lymphocyte stimulatory factor 1 [LSF-1]) is a glycosylated protein with three intra-chain disulfide bonds. IL-4 is produced by Th2 cells and participates in activation of B cells and other cell types. IL-4 also stimulates DNA synthesis, and it enhances the expression of IgE and IgG1. IL-4 decreases the production of Th1 cells, macrophages, IFN-γ, and IL-12. It is associated with severe asthma among other disorders.

Disease Research Area - Autoimmune & Inflammation

Application Area - Immunology/Inflammation

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5 plate size
50 plate size
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