Mouse interleukin-12p70 (IL-12p70) is a disulfide-linked heterodimer consisting of IL-12a (p35 subunit) and IL-12b (p40 subunit) that is mainly produced by macrophages and T lymphocytes. The IL-12a subunit also dimerizes with Ebi3 to form IL-35, and the IL-12b subunit dimerizes with IL-23a to form IL-23. IL-12, IL-23, IL-27, and IL-35 are all heterodimeric proteins and members of IL-12 cytokine family. IL-12p70 activates T cells and natural killer cells that stimulate the production of IFN-γ. It is involved in a number of disorders including peritonitis and chronic toxoplasmosis.The Mouse IL-12p70 Kit provides assay-specific components for the quantitative determination of endogenous IL-12p70 in mouse urine, serum, plasma, and cell culture supernatants.
-
-
Specifications
-
Kit Contents
-
References
-
Documentation
|
Application(s)
|
|
Cytokines & Chemokines
,
Immunology/Inflammation
|
|
Analyte(s)
|
|
IL-12p70
|
|
Species
|
|
Mouse
|
|
Instrument
|
|
MESO QuickPlex SQ 120
,
SECTOR Imager 2400
,
SECTOR Imager 6000
,
MESO SECTOR S 600
|
|
Plate Type
|
|
96-well
|
|
Capture Antibody
|
|
Rat Monoclonal
|
|
Detection Antibody
|
|
Rat Monoclonal
|
|
Dynamic Range
|
|
9.95–20 600 pg/mL
|
|
Sample Type
|
|
Serum, Plasma, Urine, Cell Culture Supernatant
|
|
Recombinant standards
|
|
Expressed in Sf21 insect cells
|
|
LLOD (Sensitivity)
|
|
9.95 pg/mL
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
Storage Statement(s)
|
|
Please refer to the product insert for the storage conditions of individual kit components.
|
|
Storage Condition
|
|
Multi-Component
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
|
2-8°C
|
1 vial
(1 vial)
|
|
|
|
|
2-8°C
|
1 vial
(75 μL)
|
|
|
|
Mouse IL-12p70 Plate
|
2-8°C
|
1 ea
(1 ea)
|
|
|
|
Diluent Assembly 5 (includes Diluent 41 - 5 mL, and Diluent 45 - 10 mL)
|
≤-10°C
|
1 ea
(1 ea)
|
|
|
|
|
RT
|
1 ea
(50 mL)
|
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
|
2-8°C
|
5 vial
(1 vial)
|
|
|
|
|
2-8°C
|
1 vial
(375 μL)
|
|
|
|
Mouse IL-12p70 Plate
|
2-8°C
|
5 ea
(1 ea)
|
|
|
|
Diluent Assembly 6 (includes Diluent 41 - 25 mL, and Diluent 45 - 50 mL)
|
≤-10°C
|
1 ea
(1 ea)
|
|
|
|
|
RT
|
1 ea
(50 mL)
|
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
|
2-8°C
|
25 vial
(1 vial)
|
|
|
|
|
2-8°C
|
5 vial
(375 μL)
|
|
|
|
Mouse IL-12p70 Plate
|
2-8°C
|
25 ea
(1 ea)
|
|
|
|
Diluent Assembly 6 (includes Diluent 41 - 25 mL, and Diluent 45 - 50 mL)
|
≤-10°C
|
5 ea
(1 ea)
|
|
|
|
|
RT
|
5 ea
(50 mL)
|
|
|
|
Title
|
Journal
|
Year
|
|
Cytokine biomarkers in tear film for primary open-angle glaucoma
|
|
|
|
A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling.
|
|
|
|
Effect of Wild-Type Shigella Species and Attenuated Shigella Vaccine Candidates on Small Intestinal Barrier Function, Antigen Trafficking, and Cytokine Release.
|
|
|
|
Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome.
|
|
|
|
Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc1638N/+ female mice.
|
|
|
|
|
View All
|
|
Product Inserts
|
|
|
|
Product Highlights
|
|
|
|
Certificate of analysis
|
|
View More
|
|
SDS
|
|
|
|
Kit Layout (Add-in)
|
|
|
Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters