R-PLEX Rat IL-10 Antibody Set

R-PLEX Rat IL-10 Antibody Set Overview
The R-PLEX Rat IL-10 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of IL-10 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Rat IL-10 Antibody Set Features
  • Measures rat IL-10 in Serum, Plasma
  • Dynamic range: 1.4 - 1,100 pg/mL
  • Median LLOD: 1.4 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Rat IL-10 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Rat IL-10 Antibody Set Calibration Curve
Calibration curve for R-PLEX Rat IL-10 Antibody Set
IL-10 Analyte

Description - Interleukin-10 (IL-10, cytokine synthesis inhibitory factor, CSIF) is produced by a variety of cell lines such as T cells, macrophages, and mast cells. The homodimer binds to two IL-10Rα subunits resulting in recruitment of two IL-10Rβ chains to initiate the signal cascades. IL-10 is involved in the inhibition of IFN-γ, IL-2, IL-3, TNF-α, TNF-β, and GM-CSF, that suppress Th1 proinflammatory responses and promote phagocytic uptake.

Application Area - Autoimmune and Inflammation, Infectious Disease

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5 plate size
50 plate size
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