R-PLEX Rat HAVCR1/KIM-1 Antibody Set

R-PLEX Rat HAVCR1/KIM-1 Antibody Set Overview
The R-PLEX Rat HAVCR1/KIM-1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of HAVCR1/KIM-1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Rat HAVCR1/KIM-1 Antibody Set Features
  • Measures rat HAVCR1/KIM-1 in urine
  • Dynamic range: 1.4 - 2,500 pg/mL
  • Median LLOD: 1.4 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Rat HAVCR1/KIM-1 Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Rat HAVCR1/KIM-1 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Rat HAVCR1/KIM-1 Antibody Set
HAVCR1/KIM-1 Analyte

Description - Hepatitis A Virus Cellular Receptor 1 (HAVCR1, KIM-1, TIM-1) is a type 1 transmembrane glycoprotein found on activated CD4+ T cells, especially Th2 cells, and dedifferentiated proximal tubule epithelial cells. In humans, HAVCR1 levels are very low or undetectable in normal samples, but following damage to the kidney, elevated levels are detected in urine, serum, and plasma. Therefore, HAVCR1 is a suitable biomarker for acute kidney injury research.

Disease Research Area - Infectious Diseases, Liver & Kidney Disease

Application Area - Kidney Injury

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5 plate size
50 plate size
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