R-PLEX Human sTfR-1 Antibody Set

R-PLEX Human sTfR-1 Antibody Set Overview
The R-PLEX Human sTfR-1 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of sTfR-1 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human sTfR-1 Antibody Set Features
  • Measures human sTfR-1 in plasma
  • Dynamic range: 1.4 - 8,000 pg/mL
  • Median LLOD: 1.4 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human sTfR-1 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human sTfR-1 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human sTfR-1 Antibody Set
sTfR-1 Analyte

Description - Soluble transferrin receptor-1 (sTfR-1, T9, TR, p90, CD71, TFR1, TRFR, IMD46, TFRC) is an extracellular portion of the transferrin receptor 1. It is inversely related to iron status, so elevated levels may indicate low iron levels, especially in inflammation, cancer, and chronic diseases. sTfR-1 is often bound to transferrin, and can be used in a quantitative assay of marrow erythropoietic activity.

Disease Research Area - Iron Deficiency, Inflammation, Cancer

Application Area - Iron Uptake

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5 plate size
50 plate size
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