R-PLEX Human Osteopontin Antibody Set

R-PLEX Human Osteopontin Antibody Set Overview
The R-PLEX Human Osteopontin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Osteopontin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Osteopontin Antibody Set Features
  • Measures human Osteopontin in plasma
  • Dynamic range: 313 - 50,000 pg/mL
  • Median LLOD: 313 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Osteopontin Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Osteopontin Antibody Set Calibration Curve
Calibration curve for R-PLEX Human Osteopontin Antibody Set
Osteopontin Analyte

Description - Osteopontin (OPN, BNSP, BSP1, ETA-1, SPP1) is a pleiotropic cytokine, expressed the most in bone, but also in kidney, heart, and epithelial tissues. It is heavily modified post-translationally. OPN is overexpressed in a variety of cancers and in patients with nephritis and acute kidney injury. OPN has been reported to be a prognostic biomarker in patients who need renal replacement therapy after acute kidney injury. It may also play a role in autoimmune diseases and have immune functions.

Disease Research Area - Cancer, Kidney Injury

Application Area - Bone Metabolism, Oncology & Cancer, Inflammation, Kidney Injury, Toxicology

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5 plate size
50 plate size
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