R-PLEX Human MPO Antibody Set

R-PLEX Human MPO Antibody Set Overview
The R-PLEX Human MPO Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of MPO in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human MPO Antibody Set Features
  • Measures human MPO in serum and plasma
  • Dynamic range: 11-200,000 pg/mL
  • Median LLOD: 11 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human MPO Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human MPO Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human MPO Antibody Set
MPO Analyte

Description - Myeloperoxidase (MPO) is produced by neutrophils and monocytes in response to leukocyte activation. These phagocytic cells undergo respiratory burst on stimulation. The extra oxygen that is consumed during this process is converted to hydrogen peroxide. MPO reacts with hydrogen peroxide to form oxidizing complexes. The oxidants have potent bactericidal and viricidal activities. MPO has also been implicated in many pathogenic states, including multiple sclerosis and Parkinson’s disease.

Disease Research Area - Infectious Diseases

Application Area - Immunology/Inflammation

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5 plate size
50 plate size
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