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This kit provides basic components for the quantitative determination of phospho-S6RP (Ser235/Ser236) in human, mouse, rat, and non-human primate whole cell lysates. Base kits generally include only MSD plates coated with the capture antibody, SULFO-TAG-labeled antibody, and MSD proprietary read buffer. (See product insert for a list of kit components). Base kits are most commonly used for high-throughput screening and assay development.
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Specifications
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Documentation
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References
Application(s)
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Phosphoproteins
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Intracellular Signaling
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Analyte(s)
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S6RP
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Species
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Human, Non-human primate, Mouse, Rat
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Plate Type
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96-well
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Instrument(s)
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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MESO QuickPlex SQ 120
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SECTOR Imager 6000
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SECTOR Imager 2400
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Capture Antibody
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Rabbit Polyclonal
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Detection Antibody
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Rabbit Polyclonal
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Kit Model
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Base
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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2-8 °C
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Product Inserts
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Datasheets
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SDS
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Title
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Journal
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Year
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Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma.
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Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo.
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Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response.
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Weekly nab-rapamycin in patients with advanced nonhematologic malignancies: final results of a phase I trial.
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mTOR kinase inhibitor potentiates apoptosis of PI3K and MEK inhibitors in diagnostically defined subpopulations.
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