| References | Journal | Year | |
A small molecule inhibitor of XIAP induces apoptosis and synergizes with vinorelbine and cisplatin in NSCLC.
Dean, E.J., Ward, T., Pinilla, C., Houghten, R., Welsh, K., Makin, G., Ranson, M., Dive, C. | Br J Cancer. | 2010 | View |
A validated assay to measure soluble IL-7 receptor shows minimal impact of IL-7 treatment.
Janot-Sardet, C., Assouline, B., Cheynier, R., Morre, M., Beq, S. | J Immunol Methods | 2010 | View |
Acute exposure of mice to high-dose ultrafine carbon black decreases susceptibility to pneumococcal pneumonia.
Tellabati, A., Fernandes, V.E., Teichert, F., Singh, R., Rylance, J., Gordon, S., Andrew, P.W., Grigg, J. | Part Fibre Toxicol. | 2010 | View |
Alterations in Cytokines and Effects of Dexamethasone Immunosuppression during Subclinical Infections of Invasive Klebsiella pneumoniae with Hypermucoviscosity Phenotype in Rhesus (Macaca mulatta) and Cynomolgus (Macaca fascicularis) Macaques.
Burke, R.L., West, M.W., Erwin-Cohen, R., Selby, E.B., Fisher, D.E., Twenhafel, N.A. | Comp Med. | 2010 | View |
Alterations of matrix metalloproteinases in healthy elderly with increased risk of prodromal Alzheimer's disease.
Stomrud, E., Bjorkqvist, M., Janciauskiene, S., Minthon, L., Hansson, O. | Alzheimers Res Ther. | 2010 | View |
An open-label, single-dose bioavailability study of the pharmacokinetics of CAT-354 after subcutaneous and intravenous administration in healthy males.
Oh, C.K., Faggioni, R., Jin, F., Roskos, L.K., Wang, B., Birrell, C., Wilson, R., Molfino, N. | British Journal of Clinical Pharmacology | 2010 | View |
Analysis of complex biomarkers for human immune-mediated disorders based on cytokine responsiveness of peripheral blood cells.
Davis, J.M. 3rd, Knutson, K.L., Strausbauch, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Matteson, E.L., Gabriel, S.E. | J Immunol Methods | 2010 | View |
Androgen Receptor-Dependent and Independent Atheroprotection by Testosterone in Male Mice.
Bourghardt, J., Wilhelmson, A.S., Alexanderson, C., De Gendt, K., Verhoeven, G., Krettek, A., Ohlsson, C., Tivesten, A. | Endocrinology | 2010 | View |
Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization.
Igawa, T., Ishii, S., Tachibana, T., Maeda, A., Higuchi, Y., Shimaoka, S., Moriyama, C., Watanabe, T., Takubo, R., Doi, Y., Wakabayashi, T., Hayasaka, A., Kadono, S., Miyazaki, T., Haraya, K., Sekimori, Y., Kojima, T., Nabuchi, Y., Aso, Y., Kawabe, Y., Hattori, K. | Nat Biotechnol. | 2010 | View |
Application of Dolichos biflorus in immunoassay detection of kidney collecting duct biomarkers.
Sourial, S., Searchfield, L., Schuppe-Koistinen, I., Betton, G.R., Riccardi, D., Price, S.A. | Biomarkers. | 2010 | View |
Applications of a planar electrochemiluminescence platform to support regulated studies of macromolecules: Benefits and limitations in assay range.
Thway, T., Macaraeg, C., Calamba, D., Patel, V., Tsoi, J., Ma, M., Lee, J., Desilva, B. | Pharm Biomed Anal. | 2010 | View |
Aß40 Oligomers Identified as a Potential Biomarker for the Diagnosis of Alzheimer's Disease.
Gao, C.M., Yam, A.Y., Wang, X., Magdangal, E., Salisbury, C., Peretz, D., Zuckermann, R.N., Connolly, M.D., Hansson, O., Minthon, L., Zetterberg, H., Blennow, K., Fedynyshyn, J.P. Allauzen, S. | PLoS ONE | 2010 | View |
Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody.
Guo, Y., Hill, A.A., Ramsey, R.C., Immermann, F.W., Corcoran, C., Young, D., Lavallie, E.R., Ryan, M., Bouchard, T., Pfeifer, R., Warner, G., Bologna, M., Bloom, L., O'Toole, M. | J Transl Med. | 2010 | View |
Assessment of DBS technology for the detection of therapeutic antibodies.
Prince PJ, Matsuda KC, Retter M, Scott G. | Bioanalysis. 2010 Aug;2(8):1449-60. | 2010 | View |
Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis.
Larsson S, Englund M, Struglics A, Lohmander LS. | Arthritis Res Ther. | 2010 | View |
AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase that induces pharmacodynamic changes and inhibits human tumor xenograft growth.
Grimshaw, K.M., Hunter, L.J., Yap, T.A., Heaton, S.P., Walton, M.I., Woodhead, S.J., Fazal, L., Reule, M., Davies, T.G., Seavers, L.C., Lock, V., Lyons, J.F., Thompson, N.T., Workman, P., Garrett, M.D. | Mol Cancer Ther. | 2010 | View |
B7-H3 Augments the Inflammatory Response and Is Associated with Human Sepsis.
Zhang, G., Wang, J., Kelly, J., Gu, G., Hou, J., Zhou, Y., Redmond, H.P., Wang, J.H., Zhang, X. | J Immunol Methods | 2010 | View |
BACE1 gene variants do not influence BACE1 activity, levels of APP or Aß isoforms in CSF in Alzheimer's disease.
Sjolander, A., Zetterberg, H., Andreasson, U., Minthon, L., Blennow, K. | Mol Neurodegener. | 2010 | View |
Beta-amyloid precursor protein mutants respond to gamma-secretase modulators.
Page, R.M., Gutsmiedl, A., Fukumori, A., Winkler, E., Haass, C., Steiner, H. | J Biol Chem. | 2010 | View |
Binding Rate Screen - A high-throughput assay in soluble lysate for prioritizing protein expression constructs.
Tian-Yu, J., Licht, S., Pardee, G., Bhat, A., Cao, Y., Gao, W., Sangalang, E., Zaror, I. | Anal Biochem. | 2010 | View |
Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity.
Rajagopalan, L.E., Davies, M.S., Kahn, L.E., Kornmeier, C.M., Shimada, H., Steiner, T.A., Zweifel, B.S., Wendling, J.M., Payne, M.A., Loeffler, R.F., Case, B.L., Norton, M.B., Parikh, M.D., Nemirovskiy, O.V., Mourey, R.J., Masferrer, J.L., Misko, T.P., Kolodziej, S.A. | J Pharmacol Exp Ther. | 2010 | View |
Biomarkers as Predictors of Response to Treatment with Motesanib in Patients with Progressive Advanced Thyroid Cancer.
Bass, M.B., Sherman, S.I., Schlumberger, M.J., Davis, M.T., Kivman, L., Khoo, H.M., Notari, K.H., Peach, M., Hei, Y.J., Patterson, S.D. | J Clin Endocrinol Metab. | 2010 | View |
Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity.
Putcha, P., Danzer, K.M., Kranich, L.R., Scott, A., Silinski, M., Mabbett, S., Hicks, C.D., Veal, J.M., Steed, P.M., Hyman, B.T., McLean, P.J. | J Pharmacol Exp Ther. | 2010 | View |
Cactin Targets the MHC Class III Protein I{kappa}B-like (I{kappa}BL) and Inhibits NF-{kappa}B and Interferon-regulatory Factor Signaling Pathways.
Atzei, P., Gargan, S., Curran, N., Moynagh, P.N. | J Biol Chem. | 2010 | View |
Capillary pressure may predict preclinical changes in the eye.
Gooding, K.M., Tooke, J.E., von Lany, H., Mitra, M., Ling, R., Ball, C.I., Mawson, D., Skinner, K., Shore, A.C. | Diabetologia | 2010 | View |