| References | Journal | Year | |
Urine Analysis and Protein Networking Identify Met as a Marker of Metastatic Prostate Cancer.
Russo, A.L., Jedlicka, K., Wernick, M., McNally, D., Kirk, M., Sproull, M., Smith, S., Shankavaram, U., Kaushal, A., Figg, W.D., Dahut, W., Citrin, D., Bottaro, D.P., Albert, P.S., Tofilon, P.J., Camphausen, K. | Clin Cancer Res. | 2009 | View |
Use of primary human cells in high-throughput screens.
Dunne A, Jowett M, Rees S. | Methods Mol Biol | 2009 | View |
Use of serum biomarkers in a diagnostic test for irritable bowel syndrome.
Lembo, A., J, Neri, B., Tolley, J., Barken, D., Carroll, S., Pan, H. | Aliment Pharmacol Ther. | 2009 | View |
Validation and comparison of two multiplex technologies, Luminex® and Mesoscale Discovery, for human cytokine profiling.
Chowdhury. F., Williams, A., Johnson, P. | J Immunol Methods | 2009 | View |
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Björkqvist, M., Wild, E.J., Thiele, J., Silvestroni, A., Andre, R., Lahiri, N., Raibon, E., Lee, R.V., Benn, C.L., Soulet, D., Magnusson, A., Woodman, B., Landles, C., Pouladi, M.A., Hayden, M.R., Khalili-Shirazi, A., Lowdell, M.W., Brundin, P., Bates, G.P., Leavitt, B.R., Möller, T., Tabrizi, S.J. | J Exp Med. | 2008 | View |
A Phase II Clinical Trial of Sorafenib in Androgen-Independent Prostate Cancer.
Dahut, W. L., Scripture, C., Posadas, E., Jain, L., Gulley, J. L., Arlen, P.M., Wright, J.J., Yu, Y., Cao L., Steinberg, S.M., Aragon-Ching, J.B., Venitz, J., Jones, E., Chen, C.C., Figg, W. D. | Clin Cancer Res. | 2008 | View |
A Protective Role for the Human SMG-1 Kinase against Tumor Necrosis Factor-alpha induced Apoptosis
Oliveira, V., Romanow, W.J., Geisen, C., Otterness, D.M., Mercurio, F., Wang, H.G., Dalton, W.S., Abraham, R.T. | J Biol Chem. | 2008 | View |
A well-based reverse-phase protein array applicable to extracts from formalin-fixed paraffin-embedded tissue.
Chung, J., Lee, S., Kris, Y., Braunschweig, T., Traicoff, J., Hewitt, S. | Proteomics Clin Appl. | 2008 | View |
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals.
Patsouris, D, Li, P.P., Thapar, D., Chapman, J., Olefsky, J.M., Neels, J.G. | Cell Metab. | 2008 | View |
Acute-Phase Serum Amyloid A as a Marker of Insulin Resistance in Mice.
Scheja, L., Hesse, B., Heike, Z., Michael, M.D., Siesky, A.M., Pospisil, H, Beisiegel, U., Seedorf, K. | Experimental Diabetes Research. | 2008 | View |
Addiction to Elevated Insulin-like Growth Factor I Receptor and Initial Modulation of the AKT Pathway Define the Responsiveness of Rhabdomyosarcoma to the Targeting Antibody.
Cao, L., Yu, Y., Darko, I., Currier, D., Mayeenuddin, L.H., Wan, X., Khanna, C., Helman, L.J. | Cancer Research. | 2008 | View |
Adherence-dependent shifts in the patterns of beta-amyloid peptides secreted by human mononuclear phagocytes.
Maler, J.M, Spitzer, P., Klafki, H.W, Esselmann, H., Bib,l M., Lewczuk, .P, Kornhuber, J., Herrmann, M., Wiltfang, J. | Brain Behavior and Immunity | 2008 | View |
Agents associated with lung inflammation induce similar responses in NCI-H292 lung epithelial cells.
Newland, N., Richter, A. | Toxicol In Vitro. | 2008 | View |
Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs.
Kienlen-Campard, P., Tasiaux, B., Van Hees, J., Li, M., Huysseune, S., Sato, T., Fei, J.Z., Aimoto S., Courtoy, P.J., Smith, S.O., Constantinescu, S.N., Octave, J.N. | J Biol Chem. | 2008 | View |
Analysis of mechanistic pathway models in drug discovery: p38 pathway.
Hendriks, B.S, Hua, F., Chabot, J.R. | Biotechnol Prog. | 2008 | View |
Antibody based Proteomics to Study Cellular Signaling Networks.
van Oostrum J, Voshol. H. | Europ Pharma Review. | 2008 | View |
Applicability of Biomarkers Is Far-Reaching.
Daniels, D. | Gen Eng Biotech News. | 2008 | View |
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
Lorenzi, P.L., Llamas, J., Gunsior, M., Ozbun, L., Reinhold, W.C., Varma, S., Ji, H., Kim, H., Hutchinson, A.A., Kohn, E.C., Goldsmith, P.K., Birrer, M.J., Weinstein, J.N. | Mol Cancer Ther. | 2008 | View |
Assessment of Unwanted Immunogenicity (Book chapter)
Wadhwa, M., Thorpe, R. | Immunogenicity of Biopharmaceuticals | 2008 | View |
Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study.
Fichorova R.N., Richardson-Harman, N., Alfano, M., Belec, L., Carbonneil, C., Chen, S., Cosentino, L., Curtis, K., Dezzutti, C.S., Donoval, B. Doncel, G.F., Donaghay, M., Grivel, J.C., Guzman, E., Hayes, M., Herold, B, Hillier, S., Lackman-Smith, C., Landay, A., Margolis, L., Mayer, K.H., Pasicznyk, J.M., Pallansch-Cokonis, M., Poli, G., Reichelderfer, P., Roberts, P., Rodriguez, I., Saidi, H., Sassi, R.R., Shattock, R., Cummins, J.E. Jr. | Anal Chem. | 2008 | View |
Biomarker Sample Collection and Handling in the Clinical Setting to Support Early-Phase Drug in Biomarker Methods in Drug Discovery and Development (Book Chapter)
Russell, C.B., Suggs, S., Robson, K.M., Kerkof, K., Kivman, L.D., Notari, K.H., Rees, W.A., Leshinsky, N., Patterson, S.D. | Humana Press. ISBN 978-1-934115-23-7
| 2008 | View |
Biomarkers of apoptosis.
Ward, T.H., Cummings, J., Dean, E., Greystoke, A., Hou, J.M., Backen, A., Ranson, M., Dive, C. | British J Cancer. | 2008 | View |
Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes.
Angell, R.M., Angell, T.D., Bamborough, P., Bamford, M.J., Chung, C.W., Cockerill, S.G., Flack, S.S., Jones K.L., Laine, D.I., Longstaff, T., Ludbrook, S., Pearson, R., Smith. K.J., Smee, P.A., Somers, D.O., Walker, A.L. | Bioorg Med Chem Lett | 2008 | View |
Cardiac troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity.
O'Brien, P.J. | Toxicology. | 2008 | View |
Challenges in translating plasma proteomics from bench to bedside: update from the NHLBI Clinical Proteomics Programs.
Gerszten, R.E., Accurso, F., Bernard, G.R., Caprioli, R.M., Klee, E.W., Klee, G.G., Kullo, I., Laguna, T.A., Roth, F.P., Sabatine, M., Srinivas, P., Wang, T.J., Ware, L.B. | Am J Physiol Lung Cell Mol Physiol. | 2008 | View |
Chronic Mouse Model of TMA-Induced Contact Hypersensitivity.
Schneider, C., Docke, W.D., Zollner, T.M., Rose, L. | J Invest Dermatol. | 2008 | View |
Coligation of the Hepatitis C Virus Receptor CD81 with CD28 Primes Naive T Lymphocytes to Acquire Type 2 Effector Function.
Serra, A., Nuti, S., Tavarini, S., Sammicheli, C., Rosa, D., Saletti, G., Soldaini, E., Abrignani, S., Wack, A. | J Immunol Methods | 2008 | View |
Combination Targeted Therapy With Sorafenib and Bevacizumab Results in Enhanced Toxicity and Antitumor Activity.
Azad, N.S., Posadas, E.M., Kwitkowski, V.E., Steinberg, S.M., Jain, L., Annunziata, C.M., Minasian, L., Sarosy, G., Kotz, H.L., Premkumar, A., Cao, L., McNally, D., Chow, C., Chen, H.X., Wright, J.J., Figg, W.D., Kohn, E.C. | J Clin Oncol. | 2008 | View |
Concurrent decrease in IL-10 with development of immune-related adverse events in a patient treated with anti-CTLA-4 therapy.
Sun, J., Schiffman, J., Raghunath, A., Ng Tang, D., Chen, H., Sharma, P. | Cancer Immun. | 2008 | View |
Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma.
Lam, L.T., Wright, G., Davis, R.E., Lenz, G., Farinha, P., Dang, L., Chan, J.W., Rosenwald, A., Gascoyne, R.D., Staudt, L.M. | Blood | 2008 | View |
CSF amyloid- 1-38 and 1-42 in FTD and AD: Biomarker performance critically depends on the detergent accessible fraction.
Bibl, M., Lewczuk, P., Esselmann, H., Mollenhauer, B., Klafki, H.W., Welge, V., Wolf, S., Trenkwalder, C., Otto, M., Kornhuber, J., Wiltfang, J. | Proteomics Clinical Applications. | 2008 | View |
Current In Vitro Kinase Assay Technologies: The Quest for a Universal Format.
Jia, Y., Quinn, C.M., Kwak, S.,Talanian, R.V. | Curr Drug Discov Technol. | 2008 | View |
Cytokine Multiplex Analysis in Inflammation and Cancer.
Young, H.A. | Methods and Protocols | 2008 | View |
Detection of ricin in food using electrochemiluminescence-based technology.
Garber, E.A., O'Brien, T.W. | J AOAC Int. | 2008 | View |
Development, Validation, and Clinical Implementation of an Assay to Measure Total Antibody Response to Naglazyme(R) (Galsulfase).
White, J.T., Martell, L.A., Van Tuyl, A., Boyer, R., Warness, L., Taniguchi, G.T., Foehr, E. | AAPS Journal. | 2008 | View |
Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold.
Herberich, B., Cao, G.Q., Chakrabarti, .PP., Falsey, J.R., Pettus, L., Rzasa, R.M., Reed, A.B., Reichelt, A., Sham, K., Thaman, M., Wurz, R.P., Xu, S., Zhang, D., Hsieh, F., Lee, M.R., Syed, R., Li, V., Grosfeld, D., Plant, M.H., Henkle, B., Sherman, L., Middleton, S., Wong, L.M., Tasker, A.S. | J Med Chem. | 2008 | View |
Dynamics of Ab Turnover and Deposition in Different APP Transgenic Mouse Models Following Gamma-Secretase Inhibition.
Abramowski, D., Wiederhold, K. Furrer, U., Jaton, A., Neuenschwander, A., Runser, M., Danner, S., Reichwald, J., Ammaturo, D., Staab, D., Stoeckli, M., Rueeger, H., Neumann, U., Staufenbiel, M. | Pharmacol Exp Ther. | 2008 | View |
Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease.
Kadir, A., Andreasen, N., Almkvist, O., Wall, A., Forsberg, A., Engler, H., Hagman, G., Lärksäter, M., Winblad, B., Zetterberg, H., Blennow, K., Langström, B., Nordberg, A. | Ann Neurol. | 2008 | View |
Effects of palifermin on antitumor activity of chemotherapeutic and biological agents in human head and neck and colorectal carcinoma xenograft models.
Brake, R., Starnes, C., Lu, J., Chen, D., Yang, S., Radinsky, R., Borges, L. | Mol Cancer Res. | 2008 | View |
Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting.
Rajendran, L., Schneider, A., Schlechtingen, G., Weidlich, S., Ries, J., Braxmeier, T., Schwille, P., Schulz, J.B., Schroeder, C., Simons, M., Jennings, G., Knölker, H.J., Simons, K. | Science. | 2008 | View |
Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category.
Luger, D., Silver, P.B., Tang, J., Cua, D., Chen, Z., Iwakura, Y., Bowman, E.P., Sgambellone, N.M., Chan, C.C., Caspi, R.R. | J Exp Med. | 2008 | View |
Electrogenerated Chemiluminescence and Its Biorelated Applications
Miao, W. | Chem Rev. | 2008 | View |
Elevated Cerebrospinal Fluid BACE1 Activity in Incipient Alzheimer Disease.
Zetterberg, H., Andreasson, U., Hansson, O., Wu, G., Sankaranarayanan, S., Andersson, M.E., Buchhave, P., Londos, E., Umek, R.M., Minthon, L., Simon, A.J., Blennow, K. | Arch Neurol. | 2008 | View |
ELISA and Multiplex Technologies for Cytokine Measurement in Inflammation and Aging Research.
Leng, S.X., McElhaney, J.E., Walston J.D., Xie D.X., Fedarko N.S., Kuchel, G.A. | J Gerontol A Biol Sci Med Sci. | 2008 | View |
Endogenous and synthetic agonists of GPR119 differ in signaling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells.
Ning, Y, O'Neill, K, Lan, H, Pang, L, Shan, L.X., Hawes B.E., Hedrick, J.A. | Br J Pharmacol. | 2008 | View |
Fragment-Based Design of Small Molecule X-Linked Inhibitor of Apoptosis Protein Inhibitors.
Huang, J.W., Zhang, Z., Wu, B., Cellitti, J.F., Zhang, X., Dahl, R., Shiau, C.W., Welsh, K., Emdadi, A., Stebbins, J.L., Reed, J.C., Pellecchia, M. | J Med Chem. | 2008 | View |
Healthy human subjects have CD4+ T cells directed against H5N1 influenza virus.
Roti, M., Yang, J., Berger, D., Huston, L., James, E.A., Kwok, W.W. | J Immunol Methods | 2008 | View |
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs.
Rottenberg, S., Jaspers, J.E., Kersbergen, A., van der Burg, E., Nygren, A.O., Zander, S.A., Derksen, P.W., de Bruin, M., Zevenhoven, J., Lau, A., Boulter, R., Cranston, A., O'Connor, M.J., Martin, N.M., Borst, P., Jonkers, J. | PNAS | 2008 | View |
HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells.
Catalfamo, M., Di Mascio, M., Hu, Z., Srinivasula, S., Thaker, V., Adelsberger, J., Rupert, A., Baseler, M., Tagaya, Y., Roby, G., Rehm, C., Follmann, D., Lane, H.C. | PNAS. | 2008 | View |
Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen.
Sasiela, C.A., Stewart, D.H., Kitagaki, J., Safiran, Y.J., Yang, Y., Weissman, A.M., Oberoi, P., Davydov, I.V., Goncharova, E., Beutler, J.A., McMahon, J.B., O'Keefe, B.R. | J Biomol Screen. | 2008 | View |