The Mouse IL-17A Antibody is a SULFO-TAG conjugated detection antibody for IL-17A. It is the same detection antibody that is in the V-PLEX Mouse IL-17A Assay. Detection antibody is supplied as a 50X concentrated solution. Mouse IL-17A (CTLA-8) is a glycosylated 17.5 kDa homodimer protein with two disulfide bonds. It induces stromal cells to produce proinflammatory and hematopoietic cytokines, and it enhances the surface expression of Intracellular adhesion molecule 1 (ICAM-1) in fibroblasts. IL-17A is a positive regulator of IL-23 production and is a key component of the Th17 pathway. IL-17A can dimerize with IL-17F. The receptor for the IL-17A, IL-17F, and IL-17A/IL-17F hetereodimer consists of IL-17RA and IL-17RC.