The Mouse IL-23 Antibody is a SULFO-TAG conjugated detection antibody for IL-23. It is the same detection antibody that is in the V-PLEX Mouse IL-23 Assay. Detection antibody is supplied as a 50X concentrated solution. Mouse IL-23 (IL-12B) is a heterodimer composed of the p40 protein that is shared with IL-12, and p19, which belongs to the IL-6 superfamily. IL-23 is secreted by dendritic cells and macrophages, is involved in Th17 cell differentiation in a pro-inflammatory setting, and induces proliferation of memory T cells.
-
-
Specifications
-
-
-
References
|
Analyte(s)
|
|
IL-23
|
|
|
Species
|
|
Mouse
|
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
|
Storage Condition
|
|
2-8 °C
|
|
|
Title
|
Journal
|
Year
|
|
Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity
|
|
|
|
Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab.
|
|
|
|
Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations.
|
|
|
|
|
|