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Immune enhancing properties of the novel Matrix-M™ adjuvant leads to potentiated immune responses to an influenza vaccine in mice.
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Immune response profiling in early rheumatoid arthritis: discovery of a novel interaction of treatment response with viral immunity.
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Immunisation with ID83 fusion protein induces antigen-specific cell mediated and humoral immune responses in cattle.
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Immunogenicity of quadrivalent human Papillomavirus vaccine in organ transplant recipients.
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Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer's disease pathology in TgSwDI and 3xTg mouse models.
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Immunosorbent analysis of ricin contamination in milk using colorimetric, chemiluminescent and electrochemiluminescent detection.
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Impact of anti-drug antibodies in preclinical pharmacokinetic assessment.
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Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birth weight.
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Improved glycemic control enhances the incretin effect in patients with type 2 diabetes.
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In Vivo luminescent imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis.
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Increased CSF levels of phosphorylated neurofilament heavy protein following bout in amateur boxers.
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Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin.
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Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice.
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Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.
Gaiottino J, Norgren N, Dobson R, Topping J, Nissim A, Malaspina A, Bestwick JP, Monsch AU, Regeniter A, Lindberg RL, Kappos L, Leppert D, Petzold A, Giovannoni G, Kuhle J. | PLoS One | 2013 | View |
Inflammation biomarkers in vaginal fluid and preterm delivery.
Taylor BD, Holzman CB, Fichorova RN, Tian Y, Jones NM, Fu W, Senagore PK. | Hum Reprod | 2013 | View |
Influence of a polyphenol-enriched protein powder on exercise-induced inflammation and oxidative stress in athletes: a randomized trial using a metabolomics approach.
Nieman DC, Gillitt ND, Knab AM, Shanely RA, Pappan KL, Jin F, Lila MA. | PLoS One | 2013 | View |
Inhibition of nuclear factor of activated T-cells (NFAT) suppresses accelerated atherosclerosis in diabetic mice.
Zetterqvist AV, Berglund LM, Blanco F, Garcia-Vaz E, Wigren M, Dunér P, Andersson AM, To F, Spegel P, Nilsson J, Bengtsson E, Gomez MF. | PLoS One | 2013 | View |
Inhibition of tumor growth and metastasis in non-small cell lung cancer by LY2801653, an inhibitor of several oncokinases, including MET.
Wu W, Bi C, Credille KM, Manro JR, Peek VL, Donoho GP, Yan L, Wijsman JA, Yan SB, Walgren RA. | Clin Cancer Res. | 2013 | View |
Insulin Secretion and Ca2+ Dynamics in β-Cells Are Regulated by PERK (EIF2AK3) in Concert with Calcineurin.
Wang R, McGrath BC, Kopp RF, Roe MW, Tang X, Chen G, Cavener DR. | J Biol Chem. | 2013 | View |
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels.
Stone K, Woods E, Szmania SM, Stephens OW, Garg TK, Barlogie B, Shaughnessy Jr JD, Hall B, Reddy M, Hoering A, Hansen E, van Rhee F. | PLoS One | 2013 | View |
Intracranial injection of Gammagard, a human IVIg, modulates the inflammatory response of the brain and lowers Aβ in APP/PS1 mice along a different time course than anti-Aβ antibodies.
Sudduth TL, Greenstein A, Wilcock DM. | J Neurosci. | 2013 | View |
Irreversible renal damage after transient Renin-Angiotensin System stimulation: involvement of an AT1-receptor mediated immune response.
Heijnen BF, Nelissen J, van Essen H, Fazzi GE, Cohen Tervaert JW, Peutz-Kootstra CJ, Mullins JJ, Schalkwijk CG, Janssen BJ, Struijker-Boudier HA. | PLoS One | 2013 | View |
Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns?
van der Burg JW, Allred EN, McElrath TF, Fichorova RN, Kuban K, O'Shea TM, Dammann O, Leviton A. | Early Hum Dev. | 2013 | View |
Isoproterenol effects evaluated in heart slices of human and rat in comparison to rat heart in vivo.
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Latent cytomegalovirus infection and innate immune function following a 75 km cycling time trial.
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Lck tyrosine kinase mediates β1-integrin signalling to regulate Schwann cell migration and myelination.
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Lipopolysaccharide-induced inflammation aggravates irradiation-induced injury to the young mouse brain.
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Loneliness promotes inflammation during acute stress.
Jaremka LM, Fagundes CP, Peng J, Bennett JM, Glaser R, Malarkey WB, Kiecolt-Glaser JK. | Psychol Sci | 2013 | View |
Lower CSF interleukin-6 predicts future depression in a population-based sample of older women followed for 17 years.
Kern S, Skoog I, Börjesson-Hanson A, Blennow K, Zetterberg H, Ostling S, Kern J, Gudmundsson P, Marlow T, Rosengren L, Waern M. | Brain Behav Immun. | 2013 | View |
Lower subjective social status exaggerates interleukin-6 responses to a laboratory stressor.
Derry HM, Fagundes CP, Andridge R, Glaser R, Malarkey WB, Kiecolt-Glaser JK. | Psychoneuroendocrinology | 2013 | View |
Maternal ileal interposition surgery confers metabolic improvements to offspring independent of effects on maternal body weight in UCD-T2DM rats.
Cummings BP, Graham JL, Stanhope KL, Chouinard ML, Havel PJ. | Obes Surg. | 2013 | View |
Mechanistic pharmacokinetic-pharmacodynamic modeling of BACE1 inhibition in monkeys: development of a predictive model for amyloid precursor protein processing.
Liu X, Wong H, Scearce-Levie K, Watts R, Coraggio M, Shin Y, Peng K, Wildsmith K, Atwal J, Mango J, Schauer S, Regal K, Hunt K, Thomas A, Siu M, Lyssikatos J, Deshmukh G, Hop C. | Drug Metab Dispos | 2013 | View |
Metabolic risk profile among overweight and obese lactating women in Sweden.
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Mice lacking epithelial I-κB kinase are protected from lipopolysaccharide and cigarette smoke extract induced inflammation.
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Microchannel acoustophoresis does not impact survival or function of microglia, leukocytes or tumor cells.
Burguillos MA, Magnusson C, Nordin M, Lenshof A, Augustsson P, Hansson MJ, Elmér E, Lilja H, Brundin P, Laurell T, Deierborg T. | PLoS One. | 2013 | View |
Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease.
Lucin KM, O'Brien CE, Bieri G, Czirr E, Mosher KI, Abbey RJ, Mastroeni DF, Rogers J, Spencer B, Masliah E, Wyss-Coray T. | Neuron | 2013 | View |
miR-199a-5p Silencing Regulates the Unfolded Protein Response in COPD and α1 Antitrypsin Deficiency.
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Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
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Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance.
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Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response.
Sampath D, Oeh J, Wyatt SK, Cao TC, Koeppen H, Eastham-Anderson J, Robillard L, Ho CC, Ross J, Zhuang G, Reslan HB, Vitorino P, Barck KH, Ungersma SE, Vernes JM, Caunt M, Van Bruggen N, Ye W, Vijapurkar U, Meng YJ, Ferrara N, Friedman LS, Carano RA. | Neoplasia | 2013 | View |
Nasal levels of soluble IL-33R ST2 and IL-16 in allergic rhinitis: inverse correlation trends with disease severity.
Baumann R, Rabaszowski M, Stenin I, Tilgner L, Gaertner-Akerboom M, Scheckenbach K, Wiltfang J, Chaker A, Schipper J, Wagenmann M. | Clinical Allergy | 2013 | View |
New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF.
Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ. | Alzheimers Dement | 2013 | View |
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
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Nucleotide-binding oligomerization domain 2 signaling promotes hyperresponsive macrophages and colitis in IL-10-deficient mice.
Jamontt J, Petit S, Clark N, Parkinson SJ, Smith P. | J Immunol | 2013 | View |
Oligoclonal bands in multiple sclerosis reactive against two herpesviruses and association with magnetic resonance imaging findings.
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Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor.
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Oral tungstate (Na2WO4) exposure reduces adaptive immune responses in mice after challenge.
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Osteoarthritis year 2013 in review: Biomarkers; reflecting before moving forward, one step at a time.
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Ozone induces glucose intolerance and systemic metabolic effects in young and aged brown Norway rats.
Bass V, Gordon CJ, Jarema KA, Macphail RC, Cascio WE, Phillips PM, Ledbetter AD, Schladweiler MC, Andrews D, Miller D, Doerfler DL, Kodavanti UP. | Toxicol Appl Pharmacol. | 2013 | View |