VEGF-C

Vascular endothelial growth factor-C (VEGF-C) is expressed most prominently in the heart, placenta, muscle, ovary, and small intestine. VEGF-C transduces different signals through the receptors VEGFR2/Flk-1 and VEGFR3/Flt-4 in vasculoangiogenesis. This growth factor is active in angiogenesis and endothelial cell growth, stimulating cell proliferation and migration; it also affects the permeability of blood vessels. VEGF-C expression is associated with hematological malignancies. In leukemia, VEGF-C, like VEGF, is a survival factor for cancer cells. Together with the expression of their receptors, VEGF and VEGF-C result in the generation of autocrine loops that may support cancer cell survival and proliferation.

 

VEGF-C Singleplex Products

Our VEGF-C immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of VEGF-C. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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Related Custom Assays

The following related assays are not in our catalog but may be available as custom orders. Custom orders are typically shipped in 3 to 6 weeks. You may request pricing and availability for the assays below using our Custom Assay Quote Request form.

  • VEGF-C - Human
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