TEK Receptor Tyrosine kinase (TIE2, TEK, VMCM, GLC3E, CD202B, Tyrosine kinase with Ig and EGF homology domains-2) is a receptor-like tyrosine kinase expressed almost exclusively in the endothelium of actively growing blood vessels. It is a receptor for the Angiopoietin family of ligands - especially Ang-1 and Ang-2, and is produced by early hematopoietic cells. The soluble form of Tie-2 (sTIE-2) which in some conditions is the entire transmembrane receptor, is found in the plasma and serum of healthy human individuals, but also correlates with come cancers including renal carcinoma.


Tie-2 Singleplex Products

Our Tie-2 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of Tie-2. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.


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