P-Cadherin

P-Cadherin (CDHP, HJMD, PCAD, CDH3) is a member of the cadherin superfamily of cell surface glycoproteins with tandem repeated extracellular domains, a single membrane portion and a conserved cytoplasmic region. P-Cadherin is involved in Ca2+-dependent cell to cell adhesion and play a fundamental role in development, embryonic morphogenesis, cytoskeletal organization, and cell migration. Mutations in the P-Cadherin gene are associated with Hypotrichosis congenital with juvenile macular dystrophy (HJMD) and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).

 

P-Cadherin Singleplex Products

Our P-Cadherin immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of P-Cadherin. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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