R-PLEX Human P-Cadherin Antibody Set

R-PLEX Human P-Cadherin Antibody Set Overview
The R-PLEX Human P-Cadherin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of P-Cadherin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human P-Cadherin Antibody Set Features
  • Measures human P-Cadherin in serum, plasma, and urine
  • Dynamic range: 75 - 100,000 pg/mL
  • Median LLOD: 75 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human P-Cadherin Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human P-Cadherin Antibody Set Calibration Curve
Calibration curve for R-PLEX Human P-Cadherin Antibody Set
P-Cadherin Analyte

Description - P-Cadherin (CDHP, HJMD, PCAD, CDH3) is a member of the cadherin superfamily of cell surface glycoproteins and is involved in Ca2+-dependent cell to cell adhesion. P-Cadherin plays a fundamental role in development, embryonic morphogenesis, cytoskeletal organization, and cell migration. Mutations in the P-Cadherin gene are associated with Hypotrichosis congenital with juvenile macular dystrophy (HJMD) and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).

Disease Research Area - Cancer, Congenital Hypotrichosis with Juvenile Macular Dystrophy (HJMD)

Application Area - Intracellular Signaling, Cell Adhesion

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5 plate size
50 plate size
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