NGAL/LCN2

Neutrophil Gelatinase-Associated Lipocalin (NGAL, Lipocalin-2, LCN2, p25, oncogene 24p3, migration stimulating factor inhibitor, MSFI) is a protein that traffics iron across cell membranes. NGAL maintains the intracellular iron concentration at normal levels. NGAL is secreted in response to interactions of toll-like receptors 4 and 9 with bacterial markers. It then sequesters iron-containing bacterial siderophores, helping to limit bacterial growth. NGAL protects MMP-9 from degradation, thus promoting the proteolytic activity of MMP-9. NGAL also increases in blood and urine within two hours of kidney injury. It is indicative of the severity of kidney injury, and may thus be a useful tool in kidney injury research.

 

NGAL/LCN2 Singleplex Products

Our NGAL/LCN2 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of NGAL/LCN2. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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NGAL/LCN2 Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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