R-PLEX Rat NGAL/LCN2 Antibody Set

R-PLEX Rat NGAL/LCN2 Antibody Set Overview
The R-PLEX Rat NGAL/LCN2 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of NGAL/LCN2 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Rat NGAL/LCN2 Antibody Set Features
  • Measures rat NGAL/LCN2 in serum and plasma
  • Dynamic range: 0.64 - 7,500 pg/mL
  • Median LLOD: 0.64 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Rat NGAL/LCN2 Antibody Set was assessed and representative data are presented below.

Figure 1. R-PLEX Rat NGAL/LCN2 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Rat NGAL/LCN2 Antibody Set
NGAL/LCN2 Analyte

Description - Neutrophil Gelatinase-Associated Lipocalin (NGAL/LCN2, 24p3, MSFI, p25, lipocalin-2) is a protein that traffics iron across cell membranes. In healthy conditions, it maintains intracellular iron concentrations at normal levels. NGAL is secreted in response to interactions of certain toll-like receptors with bacteria, then sequesters bacterial siderophores. NGAL increases in blood and urine within two hours of injury. It is also indicative of the severity of acute kidney injury, and may thus be a useful tool in kidney injury research.

Disease Research Area - Liver & Kidney Disease, Oncology

Application Area - Kidney Injury, Toxicology, Oncology & Cancer

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5 plate size
50 plate size
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