Haptoglobin

Haptoglobin (BP, HPA1S, HP2ALPHA2, HP) is an alpha-2 globulin that binds to free plasma hemoglobin (Hb) with high affinity . It consists of two alpha and two beta chains, connected by disulfide bridges. Haptoglobin levels in plasma rise in acute phase reactions. Neonates do not have measurable haptoglobin levels in serum and plasma, but levels increase by six months of age. Mutations in the Haptoglobin gene has been linked to coronary artery disease and nephropathy in type 1 diabetes, Crohn's disease, as well as susceptibility to idiopathic Parkinson's disease.

 

Haptoglobin Singleplex Products

Our Haptoglobin immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of Haptoglobin. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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