R-PLEX Human Haptoglobin Antibody Set

R-PLEX Human Haptoglobin Antibody Set Overview
The R-PLEX Human Haptoglobin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Haptoglobin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Haptoglobin Antibody Set Features
  • Measures human Haptoglobin in plasma
  • Dynamic range: 109 - 2,000,000 pg/mL
  • Median LLOD: 109 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Haptoglobin Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Haptoglobin Antibody Set Calibration Curve
Calibration curve for R-PLEX Human Haptoglobin Antibody Set
Haptoglobin Analyte

Description - Haptoglobin (BP, HPA1S, HP2ALPHA2, HP) is an alpha-2 globulin that binds to free plasma hemoglobin (Hb) with high affinity. It consists of two alpha and two beta chains, connected by disulfide bridges. Haptoglobin levels in plasma rise in acute phase reactions. Neonates do not have measurable haptoglobin levels in serum and plasma, but levels increase by six months of age. Mutations in the Haptoglobin gene has been linked to coronary artery disease and nephropathy in type 1 diabetes, Crohn's disease, as well as susceptibility to idiopathic Parkinson's disease.

Disease Research Area - Diabetes, Crohn's Disease, Parkinson's Disease

Application Area - Cardiac Biomarkers, Cardiovascular, Immunity

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5 plate size
50 plate size
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