GFAP

Glial Fibrillary Acidic Protein (GFAP, ALXDRD) is a major filament protein in astrocytes, and is frequently used as a marker to distinguish astrocytes from other glial cells, although it is also found in certain kidney, testes, pancreas, and liver cells. GFAP is part of a small family of intermediate filament proteins that are involved in cytoskeleton structure and function. GFAP helps in maintaining the blood-brain barrier, participates in mitosis, damage repair, and cell-cell communication. One GFAP mutation leads to the creation of Rosenthal fibers, a hallmark of Alexander disease. It is involved or implicated in Down's syndrome, depression, traumatic brain injury, neurodegeneration, and stroke.

 

GFAP Singleplex Products

Our GFAP immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of GFAP. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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