R-PLEX Human GFAP Antibody Set

R-PLEX Human GFAP Antibody Set Overview
The R-PLEX Human GFAP Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of GFAP in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human GFAP Antibody Set Features
  • Measures human GFAP in Serum, Plasma, CSF
  • Dynamic range: 63 - 500,000 pg/mL
  • Median LLOD: 63 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human GFAP Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human GFAP Antibody Set Calibration Curve
Calibration curve for R-PLEX Human GFAP Antibody Set
GFAP Analyte

Description - Glial Fibrillary Acidic Protein (GFAP, ALXDRD) is a major filament protein in astrocytes, and is frequently used as a marker to distinguish astrocytes from other glial cells. GFAP helps in maintaining the blood-brain barrier, and participates in mitosis, damage repair, and cell-cell communication.It is involved or implicated in Down's syndrome, depression, traumatic brain injury, neurodegeneration, and stroke.

Application Area - Neurodegenerative

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5 plate size
50 plate size
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