ENA-78

Epithelial Cell-derived Neutrophil-activating Peptide (ENA-78), also known as CXCL5, is a member of the CXC subfamily of chemokines. Full-length ENA-78 is 114 amino acids (aa) in length with a predicted molecular weight of 12 kDa. Following the removal of the signal peptide, bioactive ENA-78 is 78 aa in length. ENA-78 can be N-terminally cleaved by Cathepsin G and Chymotrypsin to ENA-74 (74 aa) and ENA-70 (70 aa), which show increased potency relative to ENA-78. ENA-78 is upregulated at sites of inflammation and is expressed by multiple hematopoietic cell types, fibroblasts, endothelial cells, vascular smooth muscle cells, and adipocytes. It acts as a chemoattractant for neutrophils, has angiogenic properties, and contributes to cancer progression.

 

ENA-78 Singleplex Products

Our ENA-78 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of ENA-78. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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ENA-78 Multiplex Products

Our multiplex panels let you process up to 10 analytes simultaneously in each well of a MULTI-SPOT microplate. They provide the same outstanding performance as our singleplex immmunoassays while saving money, sample, and time.

 

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Related Custom Assays

The following related assays are not in our catalog but may be available as custom orders. Custom orders are typically shipped in 3 to 6 weeks. You may request pricing and availability for the assays below using our Custom Assay Quote Request form.

  • ENA-78 - Human, Non-human primate
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