Corin/ATC2

Corin/ATC2 (Atrial Natriuretic Peptide-Converting Enzyme, CRN, Lrp4, PEE5, TMPRSS10) is a serine protease and a member of the trypsin superfamily. It is expressed as a transmembrane protein (type II) on cardiomyocytes where it processes pro-atrial natriuretic peptide (PANP) into its active form (ANP) through cleavage of the N-terminus. The Corin/ATC2 protein can affect blood flow and blood pressure through ANP, a strong vasodilator. Mutations in the human Corin/ATC2 gene have been reported to be associated with hypertension.

 

Corin/ATC2 Singleplex Products

Our Corin/ATC2 immunoassays provide fast, accurate, reproducible, and highly sensitive measurements of Corin/ATC2. MSD’s MULTI-ARRAY technology uses simple protocols, requires minimal sample, and quantifies analyte concentration over a wide dynamic range.

 

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