R-PLEX Human Corin/ATC2 Antibody Set

R-PLEX Human Corin/ATC2 Antibody Set Overview
The R-PLEX Human Corin/ATC2 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Corin/ATC2 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click hereR-PLEX

R-PLEX Human Corin/ATC2 Antibody Set Features
  • Measures human Corin/ATC2 in serum, plasma, and urine
  • Dynamic range: 99 - 100,000 pg/mL
  • Median LLOD: 99 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Corin/ATC2 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Corin/ATC2 Antibody Set Calibration Curve
Calibration curve for R-PLEX Human Corin/ATC2 Antibody Set
Corin/ATC2 Analyte

Description - Corin/ATC2 (CRN, Lrp4, PEE5, TMPRSS10) is a serine protease and a member of the trypsin superfamily. It is expressed as a transmembrane protein (type II) on cardiomyocytes where it processes pro-atrial natriuretic peptide (PANP) into its active form (ANP) through he cleavage of the N-terminus. The Corin/ATC2 protein can affect blood flow and blood pressure through this activation. Mutations in the human Corin/ATC2 gene have been reported to be associated with hypertension.

Disease Research Area - Cardiovascular, Hypertension

Application Area - Cardiovascular

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Order Details
Catalog No
Size
Price in USD
Qty
F210B-3
5 plate size
$800.00
F210B-8
50 plate size
$7,200.00
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