MSD is committed to providing our customers with products to advance COVID-19 research. Based on recent reports, patients infected by SARS-CoV-2 show elevated levels of inflammatory cytokines that could lead to cytokine release syndrome or "cytokine storm." We offer multiplex assays to measure key biomarkers that are involved in many inflammatory pathways.

MSD is offering pre-configured panels and individual assays for COVID-19 studies based on current recommendations from key opinion leaders and the available literature. You can also configure other panels from our full menu. Helpful references include:

1. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B. Lancet. 2020 Feb 15;395(10223):497-506.
2. Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology. Channappanavar R, Perlman S. Semin Immunopathol. 2017 Jul;39(5):529-539.
3. Coronavirus infections and immune responses. Li G, Fan Y, Lai Y, Han T, Li Z, Zhou P, Pan P, Wang W, Hu D, Liu X, Zhang Q, Wu J. J Med Virol. 2020 Apr;92(4):424-432.
4. Handbook of COVID-19 Prevention and Treatment. First Affiliated Hospital of Zhejiang University.


For Research Use Only. Not for use in diagnostic procedures.

 




V-PLEX Panels	Catalog Number	Analytes
V-PLEX Viral Panel 1 Human Kit	K15345D	IL-1β, IL-6, IL-8, TNF-α
V-PLEX Viral Panel 2 Human Kit	K15346D	IFN-γ, IL-1β, IL-4, IL-6, IL-8, IL-10, TNF-α
V-PLEX Viral Panel 3 Human Kit	K15347D	IFN-γ, IL-1β, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, TNF-α
V-PLEX Proinflammatory Panel 1 Human Kit	K15049D	IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13, TNF-α
V-PLEX Vascular Injury Panel 2 Human Kit	K15198D	CRP, ICAM-1, SAA, VCAM-1
V-PLEX Human Biomarker 54-Plex Kit	K15248D	CRP, Eotaxin, Eotaxin-3, FGF (basic), VEGFR-1/Flt-1, GM-CSF, ICAM-1, IFN-γ, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-8 (HA), IL-9, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IL-17A/F, IL-17B, IL-17C, IL-17D, IL-1RA, IL-21, IL-22, IL-23, IL-27, IL-31, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, MIP-3α, PlGF, SAA, TARC, Tie-2, TNF-α, TNF-β, TSLP, VCAM-1, VEGF-A, VEGF-C, VEGF-D
V-PLEX Viral Panel 1 NHP Kit	K15348D	IL-1β, IL-6, IL-8
V-PLEX Viral Panel 2 NHP Kit	K15349D	IFN-γ, IL-1β, IL-6, IL-8, IL-10
V-PLEX Viral Panel 3 NHP Kit	K15350D	IFN-γ, IL-1β, IL-5, IL-6, IL-8, IL-10
V-PLEX Proinflammatory Panel 1 NHP Kit	K15056D	IFN-γ, IL-1β, IL-2, IL-6, IL-8, IL-10




U-PLEX Combos	Catalog Number	Analytes
U-PLEX Viral Combo 1 Human	K15343K	G-CSF, GM-CSF, IFN-α2a, IFN-β, IFN-γ, IL-1RA, IL-1β, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12p70, IP-10, MCP1, MIP-1α, TNF-α, VEGF-A
U-PLEX Cytokine Combo 1 Human	K15045K	GM-CSF, IL-1α, IL-5, IL-7, IL-12/IL-23p40, IL-15, IL-16, IL-17A, TNF-β, VEGF-A
U-PLEX Viral Combo 1 NHP	K15344K	G-CSF, GM-CSF, IFN-α2a, IFN-γ, IL-1RA, IL-1β, IL-4, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12p70, IP-10, MCP1, MIP-1α, TNF-α, VEGF-A
U-PLEX Cytokine Combo 1 NHP	K15057K	GM-CSF, IL-1α, IL-5, IL-7, IL-12/IL-23p40, IL-15, IL-16, IL-17A, TNF-β, VEGF-A




S-PLEX Assays	Catalog Number	Analyte
S-PLEX Human G-CSF Kit	K151K3S	G-CSF
S-PLEX Human GM-CSF Kit	K151F3S	GM-CSF
S-PLEX Human IL-4 Kit	K151A3S	IL-4
S-PLEX Human IL-10 Kit	K151Y2S	IL-10
S-PLEX Human TNF-α Kit	K151E3S	TNF-α




R-PLEX Antibody Set	Catalog Number	Analyte
R-PLEX Human Ferritin Antibody Set	F21ADA	Ferritin




SARS-CoV-2 image courtesy of CDC/ Alissa Eckert, MS; Dan Higgins, MAMS