V-PLEX Plus TH17 Panel 1 Human Kit


V-PLEX Plus Th17 Panel 1 (human) Kit Overview
The V-PLEX Plus Th17 Panel 1 (human) is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Th17 Panel 1 (human) includes seven key Th17 pathway markers that are important in inflammation response and immune system regulation as well as numerous other biological processes. The kit enables the sensitive detection of native and recombinant human IL-17A (assay generation B), IL-21, IL-22, IL-23, IL-27, IL-31, and MIP-3α in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis. V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.

V-PLEX Plus Th17 Panel 1 (human) Kit Features

  • Includes seven Th17 cytokine assays (IL-17A Gen. B, IL-21, IL-22, IL-23, IL-27, IL-31, and MIP-3α) validated for measurement in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Easily customized to create subset multiplexes via the V-PLEX Assay Designer
  • LLOQs range from 0.588 pg/mL to 39 pg/mL

Typical Data
Calibration curve accuracy and precision for each analyte in the V-PLEX Th17 Panel 1 (human) Kit were assessed and the representative data are presented below.

Figure 1. V-PLEX Plus Th17 Panel 1 (human) Data
Th17 Panel 1 (human) Data
V-PLEX Plus Th17 Panel 1 (human)

Description -T cells of the Th17 lineage mediate host defense mechanisms to various infections and play a crucial role in crosstalk between the immune system and affected tissue. Th17 cells are a critical part of the immune system and act as a bridge between the innate and adaptive immune systems. Improper regulation of their proinflammatory activities contributes to numerous pathogenic conditions. They are important biomarkers for inclusion in researchers’ repertoire of cytokine and proinflammatory assays. The utility of these biomarkers can be enhanced through multiplexing which reduces assay times and sample volumes.

Disease Focus - Cancer, inflammatory bowel disease, atopic dermatitis, colitis, Crohn’s disease, rheumatoid arthritis, psoriasis, diabetes, obesity, and wound healing.

Application Area - Inflammation, cytokines and chemokines

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25 plates
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