V-PLEX Plus Rat KC/GRO Kit


Rat KC (KC/GRO)—also known as CXCL1, GROα, neutrophil-activating protein 3 (NAP-3), and melanoma growth stimulating activity alpha (MGSA-α)—is a 10.2 kDa CXC chemokine. KC/GRO is produced by fibroblasts induced by platelet-derived growth factor and expressed in macrophages and endothelial cells. It produces a biological signal by binding to its receptor, CXCR2. During inflammation, it is involved in neutrophil activation and shows hematopoietic activity. Upon secretion from bone marrow stromal cells through proteolytic cleavage, the N-terminal processed form of KC (5-72) shows highly enhanced hematopoietic activity. This chemokine and its receptor are responsible for neutrophil chemotaxis in epidemic keratoconjunctivits.The Rat KC/GRO Kit provides assay-specific components for the quantitative determination of endogenous KC/GRO in rat urine, serum, plasma, and cell culture supernatants.

  • Specifications
  • Kit Contents
  • Documentation
Order Details
Catalog No
Price in USD
1 plate
5 plates
25 plates
Customer Service/Orders

Scientific/Technical Support

Instrument Support

Company Headquarters