V-PLEX Plus Mouse IP-10 Kit


V-PLEX Plus Mouse IP-10 Kit Overview
The V-PLEX Plus Mouse IP-10 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Mouse IP-10 Kit enables the sensitive detection of native IP-10 in multiple sample types including serum, plasma, urine, cell culture supernatants, and PBMCs. To learn more about the advantages of V-PLEX assays click here.
The V-PLEX Plus Mouse IP-10 assay is also available in a multiplex combination with other related cytokines in the V-PLEX Cytokine Panel 1 (mouse) Kit (catalog # K15245G, K15245D).
All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis. V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.

V-PLEX Plus Mouse IP-10 Assay Features
  • Validated to measure mouse IP-10 in serum, plasma, cell culture supernatants, PBMCs, and urine
  • Dynamic range: 0.328 pg/mL – 650 pg/mL
  • LLOQ: 2.15 pg/mL

Typical Data
Calibration curve accuracy and precision for the V-PLEX Plus Mouse IP-10 assay were assessed and representative data are presented below.

Figure 1. V-PLEX Plus Mouse IP-10 Calibration Curve
Mouse IP-10 Calibrator Curve
Figure 2. V-PLEX Plus Mouse IP-10 Data
Mouse IP-10 Calibrator Curve Data
IP-10 Analyte

Description - Mouse interferon gamma-induced protein 10 (CXCL10, IFI10, SCYB10, INP10, gIP-10; Gene ID: 15945) is produced by monocytes and is chemotactic to monocytes, NK cells, and T lymphocytes. It has antimicrobial and antitumor effects in vivo. IP-10 shares the CXCR3 receptor that is expressed on activated T cells with the related MIG (CXCL9) and I-TAC (CXCL11) chemokines. However, antibody neutralization studies demonstrate that their signaling is non-redundant.

Disease Focus - Hepatitis C and HIV infections, atherosclerosis, type 1 diabetes, arthritis, and multiple sclerosis.

Application Area - Inflammation, cytokines, and chemokines

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25 plates
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