V-PLEX Plus Mouse IL-22 Kit


Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the  U-PLEX Mouse IL-22 Assay.

V-PLEX Plus Mouse IL-22 Kit Overview
The V-PLEX Plus Mouse IL-22 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Mouse IL-22 Kit enables the sensitive detection of native IL-22 in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays click here.

The V-PLEX Mouse IL-22 assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).

All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.
V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.

V-PLEX Mouse IL-22 Assay Features
  • Validated to measure mouse IL-22 in serum, plasma, urine, and cell culture supernatant
  • Dynamic range: 0.136 – 380 pg/mL
  • LLOQ: 1.58 pg/mL

Typical Data
Calibration curve for the V-PLEX Plus Mouse IL-22 Kit was assessed and representative data is presented below.

Figure 1. V-PLEX Plus Mouse IL-22 Kit Calibration Curve
Calibration Curve for V-PLEX Plus Mouse IL-22 Kit
IL-22 Analyte

Description - Mouse IL-22 (TIFa; IL-TIF) is a homodimer that is secreted by activated T cells – especially Th17 cells, and NK cells. IL-22 signals through a heterodimeric receptor composed of IL-22R and IL-10Rβ that is expressed primarily on epithelial cells, which it promotes to proliferate.

Disease Research Area - Autoimmune & Inflammation, Liver & Kidney Disease, Oncology

Application Area - Cytokines & Chemokines, Inflammatory Injury

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