V-PLEX Plus Mouse IL-21 Kit


Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the  U-PLEX Mouse IL-21 Assay.

V-PLEX Plus Mouse IL-21 Kit Overview
The V-PLEX Plus Mouse IL-21 Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Mouse IL-21 Kit enables the sensitive detection of IL-21 in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays click here.

The V-PLEX Mouse IL-21 assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 (mouse) Kit (catalog # K15246G, K15246D).

All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.
V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.

V-PLEX Mouse IL-21 Assay Features
  • Validated to measure mouse IL-21 in serum, plasma, urine, and cell culture supernatant
  • Dynamic range: 1.74 – 9,300 pg/mL
  • LLOQ: 12.1 pg/mL

Typical Data
Calibration curve for the V-PLEX Plus Mouse IL-21 Kit was assessed and representative data is presented below.

Figure 1. V-PLEX Plus Mouse IL-21 Kit Calibration Curve
Calibration Curve for V-PLEX Plus Mouse IL-21 Kit
IL-21 Analyte

Description - Mouse IL-21 (CVID11) is expressed by activated NK cells and Th17 cells. It stimulates proliferation of B-cells and up-regulates NK cells. IL-21 is a co-stimulator of multiple T cell biological actions including activation, proliferation and polarization. IL-21 signals through a heterodimeric receptor to the JAK/STAT pathway.

Disease Research Area - Autoimmune & Inflammation, Infectious Diseases

Application Area - Cytokines & Chemokines, Inflammatory Injury

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