Please note: This V-PLEX kit is currently being redeveloped. In the interim, MSD is offering to fulfill your order with the corresponding product on our U-PLEX platform. We recommend purchase of the
U-PLEX Mouse IL-17A Assay.
V-PLEX Plus Mouse IL-17A Kit Overview The V-PLEX Plus Mouse IL-17A Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Plus Mouse IL-17A Kit enables the sensitive detection of IL-17A in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays
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The V-PLEX Mouse IL-17A assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).
All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.
V-PLEX Plus kits also include controls, wash buffer, and plate seals for added quality and convenience.
V-PLEX Mouse IL-17A Assay Features - Validated to measure mouse IL-17A in serum, plasma, urine, and cell culture supernatant
- Dynamic range: 0.056 – 360 pg/mL
- LLOQ: 0.255 pg/mL
Typical Data Calibration curve for the V-PLEX Plus Mouse IL-17A Kit was assessed and representative data is presented below.
Figure 1. V-PLEX Plus Mouse IL-17A Kit Calibration Curve IL-17A Analyte
Description - Mouse IL-17A (CTLA-8), is a glycosylated 17.5 kDa homodimer protein with two disulfide bonds. It induces stromal cells to produce proinflammatory and hematopoietic cytokines, and it enhances the surface expression of Intracellular adhesion molecule 1 (ICAM-1) in fibroblasts. IL-17A is a positive regulator of IL-23 production and is a key component of the Th17 pathway. IL-17A can dimerize with IL-17F. The receptor for the IL-17A, IL-17F, and IL-17A/IL-17F hetereodimer consists of IL-17RA and IL-17RC.
Disease Research Area - Autoimmune & Inflammation, Infectious Diseases
Application Area - Cytokines & Chemokines, Inflammatory Injury