V-PLEX Plus Human MIP-1α Kit


Human MIP-1α (CCL3)—also known as G0/G1 switch regulatory protein 19-1 (G0S19-1), PAT464.1, SIS-beta, small-inducible cytokine A3 (SCYA3), and tonsillar lymphocyte LD78 alpha protein—is a 10.1 kDa chemokine with inflammatory and chemokinetic properties. It binds to CCR1, CCR4, and CCR5, and like MIP-1β, it is one of the major HIV suppressive factors produced by CD8+ T-cells. It occurs as a homodimer and as a heterodimer with MIP-1β. MIP-1α is involved in multiple myeloma, breast cancer, and cystic fibrosis. The Human MIP-1α Kit provides assay-specific components for the quantitative determination of endogenous MIP-1α in human urine, serum, plasma, and cell culture supernatants.

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25 plates
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