V-PLEX Plus Human IL-23 Kit

V-PLEX Human IL-23 Calibration Curve K151WWG K151WWD

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The V-PLEX platform offers analytically validated singleplex and multiplex assay kits. Developed under rigorous design control, V-PLEX kits provide accurate and reproducible results with consistency from lot to lot. The V-PLEX Plus Human IL-23 Kit enables the measurement of IL-23 in a single-analyte format. For information on multiplexing IL-23 with other analytes, please see V-PLEX Plus Th17 Panel 1 Human Kit.

V-PLEX Plus kits include controls, wash buffer, and plate seals.

Related Key Terms:
CLMF2, NKSF2, p19/IL-12p40 heterodimer, IL-12 cytokine family, interleukin, immunity, inflammation, Th17, autoimmunity, arthritis, diabetes, Crohn's disease, multiple sclerosis, psoriasis

Specifications
Documentation
References

Application(s)		Cytokines & Chemokines , Immunology/Inflammation
Analyte(s)		IL-23
Species		Human
Plate Type		96-well
Instrument(s)		MESO SECTOR S 600MM , MESO QuickPlex SQ 120MM , MESO SECTOR S 600 , MESO QuickPlex SQ 120 , SECTOR Imager 6000 , SECTOR Imager 2400
Capture Antibody		Mouse Monoclonal
Detection Antibody		Mouse Monoclonal
LLOD (Sensitivity)		0.274 pg/mL
Dynamic Range		0.274 - 3,250 pg/mL
Sample Type		Serum, Plasma, Cell Culture Supernatant, Urine
Recombinant standards		Expressed in Insect cell line
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Statement(s)		Please refer to the product insert for the storage conditions of individual kit components.
Storage Condition		Multi-Component
Gene ID(s)		51561, 3593
UniProt ID(s)		Q9NPF7, P29460
Schedule B Code		3822.19.0000

Contact Information

Customer Service/Orders
1-240-314-2795

5:00 a.m. to 8:00 p.m.
US Eastern Time

Email

Scientific/Technical Support
1-240-314-2798

8:30 a.m. to 5:30 p.m.
US Eastern Time

Email

Instrument Support
1-301-947-2057

8:30 a.m. - 5:30 p.m.
US Eastern Time

Email

Company Headquarters
1-240-314-2600
1601 Research Blvd.
Rockville, Maryland 20850-3173
USA

Product Inserts		V-PLEX TH17 Panel 1 Human Calibrator Insert V-PLEX TH17 Panel 1 Human Control Pack Insert V-PLEX TH17 Panel 1 Human Product Insert
Certificate of analysis		K0082364 K0082303 K0082261 K0081948 K0081750 K0081352 with Extension memo K0081132 K0081013 K0080886
SDS		Diluent 2, Diluent 3, Diluent 5, Diluent 7 and Diluent 8 Diluent 41, Diluent 43 and Diluent 45 MSD Calibrators and Controls Read Buffer T (4x), Read Buffer S (4x) and Read Buffer S (1x) Wash Buffer (20X)
Scientific Posters		Development and Characterization of V-PLEX TH17 Cytokine Assays - WIRM 2017

Title	Journal	Year
Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity Bain KA, McDonald E, Moffat F, Tutino M, Castelino M, Barton A, Cavanagh J, Ijaz UZ, Siebert S, McInnes IB, Astrand A, Holmes S, Milling SWF	British Journal of Dermatology	2019
Protection Against Lethal Multidrug-Resistant Bacterial Infections Using Macrophage Cell Therapy Robert Tacke, Josh Sun, Satoshi Uchiyama, Anya Polovina, Deborah G. Nguyen, Victor Nizet, Stijn van der Veen	Infectious Microbes & Diseases	2019
Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab. Luo, J., Wu, S.J., Lacy, E.R., Orlovsky, Y., Baker, A., Teplyakov, A., Obmolova, G., Heavner, G.A., Richter, H.T., Benson, J.	J Mol Biol.	2010
Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations. Gourh, P., Arnett, F.C., Assassi, S., Tan, F.K., Huang, M., Diekman, L., Mayes, M.D., Reveille, J.D., Agarwal, S.K.	Arthritis Res Ther.	2009

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