V-PLEX Mouse MIP-3α Kit


V-PLEX Mouse MIP-3α Kit Overview
The V-PLEX Mouse MIP-3α Kit is optimized for long-term and multi-site biomarker studies that require reliable, reproducible results with lot-to-lot consistency. The V-PLEX Mouse MIP-3α Kit enables the sensitive detection of MIP-3α in multiple sample types including serum, plasma, urine, and cell culture supernatant. To learn more about the advantages of V-PLEX assays click here.

The V-PLEX Mouse MIP-3α assay is available as an individual assay as well as in a multiplex combination with other Th17-related analytes in the V-PLEX Th17 Panel 1 Mouse Kit (catalog # K15246G, K15246D).

All V-PLEX kits come with coated plates, calibrators, labeled detection antibodies, optimized diluents, a comprehensive product insert, and a certificate of analysis.

V-PLEX Mouse MIP-3α Assay Features
  • Validated to measure mouse MIP-3α in serum, plasma, urine, and cell culture supernatant
  • Dynamic range: 0.389 – 530 pg/mL
  • LLOQ: 3.42 pg/mL

Typical Data
Calibration curve for the V-PLEX Mouse MIP-3α Kit was assessed and representative data is presented below.

Figure 1. V-PLEX Mouse MIP-3α Kit Calibration Curve
Calibration Curve for V-PLEX Mouse MIP-3α  Kit
MIP-3α Analyte

Description - Mouse macrophage inflammatory protein 3α (CCL20, SCYA20, LARC, CKb4; Gene ID: 20297) is a chemokine with inflammatory and homeostatic functions. Initially identified in the liver, MIP-3α is expressed in lymphatic tissue, lung tissue, macrophages, dendritic cells, B- and T- lymphocytes, and eosinophilic granulocytes as well as in normal colon, pancreas, prostate, uterine cervix, and skin. MIP-3α is a ligand for the CCR6 receptor; it is also chemotactic for CCR6+ cells such as dendritic cells and Th17 T cells.

Disease Research Area - Autoimmune & Inflammation, Cardiovascular Disease, Metabolic Diseases, Oncology

Application Area - Cytokines & Chemokines, Inflammatory Injury

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1 plate
5 plates
25 plates
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